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<p class="BATitle">Benzimidazolium picrate single crystal: Synthesis, growth, characterization and their biological activity</p>

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Title Statement <p class="BATitle">Benzimidazolium picrate single crystal: Synthesis, growth, characterization and their biological activity</p>
 
Added Entry - Uncontrolled Name Vadivelan, Ganesan ; Department of Chemistry, Kongunadu Arts and Science College, Coimbatore, Tamil Nadu, India
Gohulavani, Grahandurai ; Department of Chemistry, Ethiraj College for Women, Chennai, Tamil Nadu, India
Saravanabhavan, Munusamy ; Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, Tamil Nadu, India
Murugesan, Venkatesan ; Krishna Arts and Science College, Krishnagiri, Tamil Nadu, India
Sekar, Marimuthu ; Department of Chemistry, Sri Ramakrishna Mission Vidyalaya College of Arts and Science, Coimbatore, Tamil Nadu, India
 
Uncontrolled Index Term Benzimidazolium picrate; Charge-transfer complex; 2,2-Diphenyl-2-picryl-hydrazyl
 
Summary, etc. <p style="text-align: justify;">Knowledge on charge-transfer complexes of drugs is important to understand the drug-receptor binding mechanism. Here, we have been synthesized the organic charge transfer complex of Benzimidazolium picrate (BP) and confirmed its molecular structure and carbon skeleton by <sup>1</sup>H and <sup>13</sup>C NMR spectral analysis. Asymmetric unit of BP consists of one benzimidazolium cation and a monovalent anion of picric acid. Decomposition pattern and thermal stability BP have been investigated using TG/DTA analysis. The interaction of the compound with calf thymus DNA is investigated by electronic absorption spectroscopy which indicates that the compound could interact with DNA through intercalation. The CT complex demonstrated significant free radical scavenging with 2,2-diphenyl-2-picryl-hydrazyl. The BP complex has been also screened for its antimicrobial activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2020-10-06 15:05:21
 
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http://op.niscair.res.in/index.php/IJCA/article/view/41269
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 59, ##issue.no## 9 (2020): INDIAN JOURNAL OF CHEMISTRY - SECTION A
 
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