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<p class="BATitle">Fabrication of polycaprolactone/β-tricalciumphosphate based nano scaffolds using electrospinning method for biomedical applications</p>

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Title Statement <p class="BATitle">Fabrication of polycaprolactone/β-tricalciumphosphate based nano scaffolds using electrospinning method for biomedical applications</p>
 
Added Entry - Uncontrolled Name Seethalakshmi, K ; Department of Chemistry, Rajalakshmi Engineering College, Thandalam, Chennai 602 105, Tamil Nadu, India
Kaviya, M ; Department of Analytical Chemistry, University of Madras, Maraimalai campus, Guindy, Chennai 600 025, Tamil Nadu, India
Sundara, M Ganeasan; Department of Analytical Chemistry, University of Madras, Maraimalai campus, Guindy, Chennai 600 025, Tamil Nadu, India
Venkatachalapathy, B ; Department of Chemistry, Easwari Engineering College, Ramapuram, Chennai 600 089, Tamil Nadu, India
Veerabadran, K M; Department of Chemistry, Anna University, MIT Campus, Chrompet, Chennai 600 044, Tamil Nadu, India
Sridhar, T M; Department of Analytical Chemistry, University of Madras, Maraimalai campus, Guindy, Chennai 600 025, Tamil Nadu, India
 
Uncontrolled Index Term Bone tissue engineering; Electrospinning; PCL/β-TCP hybrid nanoscaffolds; Nanocomposites; Osteoconductive
 
Summary, etc. <p style="text-align: justify;">In this study, we have focused on preparation, fabrication and characterization of polycaprolactone and beta tricalcium phosphate (PCL/β-TCP) composite scaffolds that are used for bone tissue engineering applications. The electrospun composites have been characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM). The developed scaffolds are effectively simulated the morphology, mechanical property and bioactivity for load-bearing tissue engineering applications. The bioactivity of the scaffolds has been evaluated with <em>in vitro</em> cell adhesion and growth studies. The results confirm the nontoxic behaviour of the composite biomaterials and developed scaffolds with MG-63 osteoblast-like cell line. The synthesized scaffolds have shown promising bioactivity with the growth as well as proliferation of new bone cells with considerable osteoconductive properties. The nanoscaffolds possess better physical properties and support high cell adhesion suggesting their application in bone tissue engineering field.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2020-10-06 15:05:21
 
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http://op.niscair.res.in/index.php/IJCA/article/view/41267
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 59, ##issue.no## 9 (2020): INDIAN JOURNAL OF CHEMISTRY - SECTION A
 
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