<p><span style="font-size: x-small;">Study of Kirkwood-Buff integrals of selected polar and nonpolar amino acids in aqueous-streptomycin sulphate solutions at 298.15 K</span></p><br />
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Title Statement |
<p><span style="font-size: x-small;">Study of Kirkwood-Buff integrals of selected polar and nonpolar amino acids in aqueous-streptomycin sulphate solutions at 298.15 K</span></p><br /> |
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Added Entry - Uncontrolled Name |
NAIN, ANIL KUMAR; Dyal Singh College (University of Delhi) Bisht, Yogita ; Hansraj College (University of Delhi) |
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Uncontrolled Index Term |
Physical Chemistry Kirkwood-Buff integrals, Amino acids, Streptomycin sulphate, Apparent molar volume, Density, Ultrasonic speed |
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Summary, etc. |
The Kirkwood-Buff (K-B) integrals can play pivotal role in understanding the physiochemical action of drugs on proteins. The Kirkwood-Buff theory can be used to characterize the intermolecular interactions of amino acids with drug by directly calculating G<sub>11</sub>, G<sub>22</sub> and G<sub>12</sub> parameters which represents solute-solute, solvent-solvent and solute-solvent interaction respectively. The K-B integrals of nonpolar amino acids glycine, <em>l</em>-alanine, <em>l</em>-valine, <em>l</em>-isoleucine and polar amino acids <em>l</em>-histidine and <em>l</em>-arginine in aqueous-streptomycin sulphate solutions (1% and 2% streptomycin sulphate in water, w/w) have been calculated from experimental data of ultrasonic speed and density at 298.15 K. All the results obtained by theoretical calculations are in good agreement with that of experimental results. |
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Publication, Distribution, Etc. |
Indian Journal of Chemistry -Section A (IJCA) 2020-10-12 16:00:32 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJCA/article/view/22196 |
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Data Source Entry |
Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 58, ##issue.no## 2 (2019): INDIAN JOURNAL OF CHEMISTRY- SECTION A |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJCA/article/download/22196/465469423 http://op.niscair.res.in/index.php/IJCA/article/download/22196/465469424 http://op.niscair.res.in/index.php/IJCA/article/download/22196/465469425 |
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