Microwave assisted, BF3.OEt2 catalyzed efficient synthesis of tosylhydrazones and SC-XRD study of two of the synthesized tosylhydrazones
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Title |
Microwave assisted, BF3.OEt2 catalyzed efficient synthesis of tosylhydrazones and SC-XRD study of two of the synthesized tosylhydrazones
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Creator |
Bhuyan, Pubanita
Bhuyan, Amar Jyoti Dutta, Bidyut Jyoti Bharali, Sourav Jyoti Saikia, Lakhinath |
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Subject |
Tosylhydrazones
Microwave assisted reaction BF3.OEt2 Carbonyl compounds Tosylhydrazine |
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Description |
1579-1585
A highly efficient methodology for transformation of carbonyl compounds to their corresponding tosylhydrazones under microwave irradiation in presence of BF3.OEt2 catalyst has been developed and described here. The methodology is highly prospective for tosylhydrazone synthesis especially of diaryl ketones, as already existing procedures are found to be less effective for the same. Seventeen carbonyl compounds have been studied and found to deliver their corresponding products in excellent yield (92-98%). The products crystallize out from the reaction mixture during cooling at room temperature which excludes further purification processes. Single crystal X-ray diffraction (SC-XRD) analysis of two of the synthesized tosylhydrazones have been carried out and reported here. |
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Date |
2020-10-13T06:04:12Z
2020-10-13T06:04:12Z 2020-10 |
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Type |
Article
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Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55462 |
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Language |
en_US
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Rights |
CC Attribution-Noncommercial-No Derivative Works 2.5 India
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Publisher |
NISCAIR-CSIR, India
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Source |
IJC-B Vol.59B(10) [October 2020]
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