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<p>A novel electrochemical biosensor for the detection of ethambutol</p>

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Title Statement <p>A novel electrochemical biosensor for the detection of ethambutol</p>
 
Added Entry - Uncontrolled Name Rajasekhar, Chokkareddy ; Durban University of Technology
Redhi, Gan G; Durban University of Technology
Bhajanthri, Natesh Kumar ; Durban University of Technology
Durban University of Technology
 
Uncontrolled Index Term analytical chemistry
Electroanalytical chemistry, Biosensors, Ethambutol, Cyclic voltammetry, Different pulse voltammetry
 
Summary, etc. <p>A glassy carbon electrode (GCE) has been fabricated with zinc oxide nanoparticles (ZnONPs) and reduced graphene oxide (RGO) immobilized with horseradish peroxidase enzyme (HRP) for the voltammetric determination of ethambutol. Electrochemical behaviour of ethambutol has been studied with cyclic voltammetry and differential pulse voltammetry. The HRP-ZnONPs-RGO-GCE exhibits high electrooxidation of ethambutol in phosphate buffer solution at pH 7.0 and the electrochemical signal is significantly enhanced. In addition, the proposed biosensor has been characterized by transmission electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. The HRP-ZnONPs-RGO-GCE shows an oxidation peak at –0.2 V with CV. Under the optimized conditions, the DPV technique gave good limit of detection and limit of quantification values of 0.0214 μM and 0.6713 μM respectively. The HRP-ZnONPs-RGO-GCE shows excellent background current stability and gives reliable performance with pharmaceutical samples in the terms of sensitivity, reproducibility and repeatability.</p> <p><strong> </strong></p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2020-10-19 14:04:12
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJCA/article/view/20605
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 57, ##issue.no## 7 (2018): INDIAN JOURNAL OF CHEMISTRY- SECTION A
 
Language Note en
 
Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCA/article/download/20605/63399
http://op.niscair.res.in/index.php/IJCA/article/download/20605/63631
http://op.niscair.res.in/index.php/IJCA/article/download/20605/465465354
http://op.niscair.res.in/index.php/IJCA/article/download/20605/465469546
 
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