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<p>Effect of <em>γ</em>-radiation on structure, photoluminescence properties and <em>in vitro</em> cytotoxicity of LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+ </sup>phosphor</p>

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Title Statement <p>Effect of <em>γ</em>-radiation on structure, photoluminescence properties and <em>in vitro</em> cytotoxicity of LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+ </sup>phosphor</p>
 
Added Entry - Uncontrolled Name Mukkamala, Saratchandra Babu; GITAM University
UGC-DAE consortium for Scientific Research, Kolkata Centre, India
 
Uncontrolled Index Term Inorganic Chemistry; Material Chemistry
Phosphors, Hydrothermal synthesis, Luminescence, Gamma radiations, Cytotoxicity, Lanthanum phosphates, Rare earths, Cerium, Terbium
 
Summary, etc. <p style="text-align: justify;">Lauric acid capped<strong> </strong>Ce<sup>3+</sup> sensitized LaPO<sub>4</sub>:Tb<sup>3+</sup> nanorods have been synthesized by hydrothermal route at 150 °C. The structure, stability and luminescent properties have been examined by TEM, TG/DTA, FT-IR, powder X-ray diffraction and PL spectral data. Cytotoxic activity has been examined by MTT assay. The LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+</sup> phosphor exhibits four emission peaks at 485, 551, 583 and 619 nm corresponding to <sup>5</sup><em>D</em><sub>4</sub>→<sup>7</sup><em>F</em><sub>6</sub>, <sup>5</sup><em>D</em><sub>4</sub>→<sup>7</sup><em>F</em><sub>5,</sub> <sup>5</sup><em>D</em><sub>4</sub>→<sup>7</sup><em>F</em><sub>4</sub> and <sup>5</sup><em>D</em><sub>4</sub>→<sup>7</sup><em>F</em><sub>3</sub> transitions, respectively. The influence of γ-radiation on photoluminescence properties of LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+</sup> phosphor has also been examined at 5 and 300 kGy. Furthermore, LaPO<sub>4</sub> and LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+</sup> phosphors exhibit 80–82% cytotoxic effect against breast cancer cell lines, MDA-MB 231 and MCF-7. The IC<sub>50</sub> values for LaPO<sub>4</sub> and LaPO<sub>4</sub>:Tb<sup>3+</sup>,Ce<sup>3+</sup> phosphors are 17.2 and 13.5 µg/mL against MCF-7 and 21.5 and 15.0 µg/mL against MDA-MB 231 cell line, respectively.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2020-10-19 13:04:43
 
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http://op.niscair.res.in/index.php/IJCA/article/view/18087
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 57, ##issue.no## 6 (2018): INDIAN JOURNAL OF CHEMISTRY- SECTION A
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCA/article/download/18087/54426
http://op.niscair.res.in/index.php/IJCA/article/download/18087/57660
http://op.niscair.res.in/index.php/IJCA/article/download/18087/57661
 
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