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<p><strong>Kidney damage in COVID-19 patients with or without chronic kidney disease: Analysis of clinical characteristics and related risk factors</strong></p>

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Title Statement <p><strong>Kidney damage in COVID-19 patients with or without chronic kidney disease: Analysis of clinical characteristics and related risk factors</strong></p>
 
Added Entry - Uncontrolled Name Liu, Hong
Wang, Huanlan
Tu, Can
Mao, Dongdong
Hu, Yanglin
Zou, Rong
Min, Yonglong
Xiong, Fei
Su, Wen
 
Uncontrolled Index Term Acute kidney injury (AKI); Anemia, CKD; Hypersensitive C-reactive protein; Serum creatinine; Cardiac troponin I
 
Summary, etc. COVID-19 poses more risk to patients who already suffer from other diseases, particularly respiratory disorder. In this study, we analyzed the clinical characteristics and related risk factors during hospitalization of COVID-19 patients admitted with kidney damage. A total of 102 COVID-19 patients with kidney damage [irrespective of their chronic kidney disease (CKD) history] during hospitalization were included in this study. The patients were divided into a core group and a group who developed critical illness or death. Clinical data included age, gender, length of hospitalization, clinical manifestations, medical history, hypersensitive C-reactive protein (hs -CRP), high serum creatinine, low cardiac troponin I (cTnI), and hemoglobin. Univariate and multivariate logistic regression models were used to analyze the risk factors of patients' outcome. Among the outcomes, 75 patients (73.53%) were cured, 27 (26.47%) developed to critical illness or death, 20 (19.61%) of them died. A total of 36 (4.26%) out of 845 COVID-19 patients, developed acute kidney injury (AKI). Decreased oxygen saturation, elevated hs-CRP, elevated serum creatinine, elevated cTnI, and anemia were related factors for COVID-19 patients who developed to critical illness or death (<em>P</em> &lt;0.05). Decreased oxygen saturation, elevated hs-CRP and anemia were not independent factors, but elevated serum creatinine and elevated cTnI were independent factors for COVID-19 patients who developed to critical illness or death (<em>P</em> &lt;0.05). Among COVID-19 patients with or without CKD but with kidney damage during hospitalization, patients with elevated serum creatinine and elevated TnI, more likely to developed critical illness or death.
 
Publication, Distribution, Etc. Indian Journal of Experimental Biology (IJEB)
2020-10-29 16:49:53
 
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http://op.niscair.res.in/index.php/IJEB/article/view/42370
 
Data Source Entry Indian Journal of Experimental Biology (IJEB); ##issue.vol## 58, ##issue.no## 11 (2020): IJEB [November 2020]
 
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