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First report of anti-inflammatory chromenyl derivatives from the spineless cuttlefish Sepiella inermis

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Relation http://eprints.cmfri.org.in/14572/
https://www.tandfonline.com/doi/abs/10.1080/14786419.2018.1539981
https://doi.org/10.1080/14786419.2018.1539981
 
Title First report of anti-inflammatory chromenyl
derivatives from the spineless cuttlefish Sepiella
inermis
 
Creator Krishnan, Soumya
Chakraborty, Kajal
Joy, Minju
 
Subject Bioactive compound
New record
Cephalopods
Fish Biotechnology
 
Description The spineless cuttlefish Sepiella inermis encompasses a major share in the marine fisheries sector, and represents as a culinary delicacy in many cultures. Bioactivity-guided fractionation of methanol:ethyl acetate (MeOH:EtOAc, 1:1) extract of the edible parts of the species ensued in identification of two hexahydro chromenyl analogues namely, methyl 7-ethyl-hexahydro-8a-methyl-2H-chromene-4-carboxylate (1) and methyl 1-acetoxy-hexahydro-3-methyl-3-propyl-1H-isochromene-4-carboxylate (2). The isolated metabolites were checked for their radical scavenging and anti-inflammatory potentials by selective in vitro models. The isochromenyl derivative exhibited potential 2,2-diphenyl-1-picryl-hydrazil and 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (IC50 
 
Publisher Taylor and Francis
 
Date 2020
 
Type Article
PeerReviewed
 
Format text
 
Language en
 
Identifier http://eprints.cmfri.org.in/14572/1/Natural%20Product%20Research_2020_Kajal%20Chakraborty_First%20report%20of%20anti%20inflammatory%20chromenyl%20derivatives%20from%20the%20spineless%20cuttlefish%20Sepiella%20inermis.pdf
Krishnan, Soumya and Chakraborty, Kajal and Joy, Minju (2020) First report of anti-inflammatory chromenyl derivatives from the spineless cuttlefish Sepiella inermis. Natural Product Research, 34 (17). pp. 2437-2447. ISSN 1478-6427 (Online)