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<span lang="EN-GB">Condensation of nicotinaldehydes with acetophenones and NH<sub>4</sub>OAc</span><span lang="EN-GB">: A convenient synthesis and biological activities of 2',6'-diphenyl-3,4'-bipyridines</span>

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Title Statement <span lang="EN-GB">Condensation of nicotinaldehydes with acetophenones and NH<sub>4</sub>OAc</span><span lang="EN-GB">: A convenient synthesis and biological activities of 2',6'-diphenyl-3,4'-bipyridines</span>
 
Added Entry - Uncontrolled Name Bhimapaka, China Raju ; CSIR-Indian Institute of Chemical Technology, Hyderabad
Begum, Shahnaz ; Department of Organic Synthesis & Process Chemistry CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Rajeswari, B Uma ; Department of Organic Synthesis & Process Chemistry CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Prakasham, R S ; Department of Organic Synthesis & Process Chemistry CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Zehra, A ; Centre for Natural Products & Traditional Knowledge, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Tiwari, A K ; Centre for Natural Products & Traditional Knowledge, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
 
Uncontrolled Index Term Nicotinaldehydes, 2',6'-diphenyl-3,4'-bipyridines, anti-microbial activity, α-glucosidase inhibitory activity
 
Summary, etc. <p>2',6'-Diphenyl-3,4'-bipyridines <strong>3a-t</strong> have been achieved by the three-component, one-pot reaction of nicotinaldehydes <strong>1a-b</strong>, acetophenones <strong>2a-j</strong> and anhydrous ammonium acetate under solvent free conditions at 120°C. All the prepared compounds <strong>3a-t</strong> have been screened for anti-microbial, free-radical scavenging and α-glucosidase inhibitory activities. Compounds <strong>3m-r </strong>have shown anti-bacterial activity and compounds <strong>3m-n</strong> identified as anti-fungal agents. Compounds <strong>3d</strong>, <strong>3h</strong>, <strong>3m</strong> and <strong>3r-s </strong>have shown α-glucosidase inhibitory activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2020-11-04 15:59:01
 
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http://op.niscair.res.in/index.php/IJCB/article/view/32043
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 59, ##issue.no## 7 (2020): INDIAN JOURNAL OF CHEMISTRY - SECTION B
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/32043/465498769
http://op.niscair.res.in/index.php/IJCB/article/download/32043/465517443
 
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