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Condensation of nicotinaldehydes with phenylethanones: A convenient synthesis and biological activities of chalcones

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Title Statement Condensation of nicotinaldehydes with phenylethanones: A convenient synthesis and biological activities of chalcones
 
Added Entry - Uncontrolled Name Bhimapaka, China Raju ; Department of Organic Synthesis & Process Chemistry
Somanaboina, Ramya
Kolla, Sai Teja
Kurma, Siva Hariprasad
Ali, Zehra
Ganji, Praveena
Tiwari, Ashok Kumar
Reddy Shetty, Prakasham
 
Uncontrolled Index Term Nicotinaldehydes, chalcones, anti-microbial activity, α-glucosidase inhibitory activity
 
Summary, etc. Claisen-Schmidt condensation of nicotinaldehydes 1a-e with various phenylethanones 2a-d in the presence of base at room temperature have provided chalcones 3a-t. All the synthesized compounds have been evaluated for their anti-microbial, free-radical scavenging and α-glucosidase inhibitory activities. Compounds 3d and 3h have been identified as potent anti-fungal and moderate anti-bacterial agents. Compounds 3c, 3h, 3k-m and 3q have shown α-glucosidase inhibitory activity.
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2020-11-04 15:59:01
 
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http://op.niscair.res.in/index.php/IJCB/article/view/27943
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 59, ##issue.no## 7 (2020): INDIAN JOURNAL OF CHEMISTRY - SECTION B
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/27943/465486198
http://op.niscair.res.in/index.php/IJCB/article/download/27943/465486370
http://op.niscair.res.in/index.php/IJCB/article/download/27943/465486371
 
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