<p style="text-align: justify;"><span lang="EN-GB">Molecular interactions studies of doxycycline hyclate in water, aqueous L-phenylalanine and glycyl glycine at different temperatures by using volumetric, ultrasonic and viscometric parameters</span></p>
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Title Statement |
<p style="text-align: justify;"><span lang="EN-GB">Molecular interactions studies of doxycycline hyclate in water, aqueous L-phenylalanine and glycyl glycine at different temperatures by using volumetric, ultrasonic and viscometric parameters</span></p> |
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Added Entry - Uncontrolled Name |
Thakur, Poonam ; HPU Sharma, Shashi Kant; Department of Chemistry, Himachal Pradesh University, Summer Hill, Shimla-171005, Himachal Pradesh, India |
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Uncontrolled Index Term |
thermodynamics Jones-Dole B-coefficient, Partial molar volume, Partial molar adiabatic compressibility, Standard partial molar volume of transfer, Transition state theory, Walden Product |
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Summary, etc. |
The density, sound velocity and viscosity of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine have been determined at different temperatures (305.15, 310.15, 315.15 and 320.15) K. The calculated values of partial molar volume (V_ϕ^o), standard partial molar volume of transfer (〖Δ_tr V〗_ϕ^o), partial molar adiabatic compressibility (κ_(ϕ,s)^o) and partial molar adiabatic compressibility of transfer (〖Δ_tr κ〗_(ϕ,s)^o) for doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine infer the dominance of ion-hydrophilic interactions over hydrophobic-hydrophobic interactions. The Jones-Dole viscosity B-coefficient, viscosity B-coefficient of transfer (ΔtrB), free energy of activation of viscous flow per mole of pure solvent (〖Δμ〗_1^(o*)) and solute (〖Δμ〗_2^(o*) ), respectively, activation entropy (〖ΔS〗_2^(o*)) and activation enthalpy (〖ΔH〗_2^(o*)) of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine also have been calculated using viscosity data. The structure making and breaking behaviour of doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine are obtained from the values of Hepler’s constant i.e.((δ^2 V_ϕ^o)/(δT^2 )) and (dB/dT). The presence and absence of caging effect has been studied with the help of partial molar adiabatic expansibility (E_ϕ^o). The isobaric thermal expansion coefficient (α^o= (E_ϕ^o)/(V_ϕ^o )), intermolecular free length and acoustic impedance for doxycycline hyclate in water, aqueous solution of L-phenylalanine and aqueous solution of glycyl glycine also have been determined. |
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Publication, Distribution, Etc. |
Indian Journal of Chemistry -Section A (IJCA) 2020-11-05 10:09:35 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJCA/article/view/24772 |
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Data Source Entry |
Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 59, ##issue.no## 11 (2020): INDIAN JOURNAL OF CHEMISTRY - SECTION A |
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Language Note |
en |
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Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJCA/article/download/24772/465477319 |
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