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3,6-Di(pyridin-2-yl)-1,2,4,5-s-tetrazine capped-gold nanoparticles as an efficient antibacterialagent against gram-positive Bacillus subtilis

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Title 3,6-Di(pyridin-2-yl)-1,2,4,5-s-tetrazine capped-gold nanoparticles as an efficient antibacterialagent against gram-positive Bacillus subtilis
 
Creator Joardar, Sutapa
Ray, Shounak
 
Subject Antibacterial activity
Antibacterial mechanism
Gold nanoparticles
TEM analysis
 
Description 1627-1631
In current work, we present 3,6-di(pyridin-2-yl)-1,2,4,5-s-tetrazine (pytz) capped gold nanoparticles (TzAuNPs) as an potent antibacterial agent against Gram-positive bacteria. The antibacterial properties of TzAuNPs have been studied using Gram-positive Bacillus subtilis (ATCC 11774) by the plate count method and TzAuNPs is found to be highly effective against the strain. Furthermore, TzAuNPs also show significantly better antimicrobial activity against the bacterial strain when compared to pytz. The effect of TzAuNPs on the bacterial cell wall is also investigated by TEM analysis. This new antimicrobial material could be promising in future for the treatment infectious diseases caused by Gram-positive bacteria.
 
Date 2020-11-02T08:21:54Z
2020-11-02T08:21:54Z
2020-11
 
Type Article
 
Identifier 0975-0975(Online); 0376-4710(Print)
http://nopr.niscair.res.in/handle/123456789/55591
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJC-A Vol.59A(11) [November 2020]