Record Details

Antioxidant and anticholinergic properties of Citrus sinensis (L.) Osbeck (Rutaceae) essential oil in mice hippocampus

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Antioxidant and anticholinergic properties of Citrus sinensis (L.) Osbeck (Rutaceae) essential oil in mice hippocampus
 
Creator Feitosa, C M
Cardoso, M F K
Oliveira, L S G
Figueredo, J
Melo, C H S
Rashed, K
 
Subject Antiacetylcholinesterase activity
Antioxidant activity
Citrus sinensis
Essential oil
 
Description 199-205
This study evaluated anti-acetylcholinesterase and antioxidant potentials in mice hippocampus treated with essential oils (EO) of Citrus sinensis (L.) Osbeck (orange) in vitro and in vivo. The acetylcholinesterase (AChE) activity was evaluated by using an adapted spectrophotometric method by Ellman after administration (30 consecutive days) in albino mice at doses of 50.00 mg/kg (EO 50), 100.00 mg/kg (EO 100) and 200.00 mg/kg (EO 200). The results showed that there was a significant decrease on enzymatic activity of AChE in mice hippocampus treated with essential oil of C. sinensis at doses of 50.00 mg/kg (vehicle= 9.89±0.19, OE 50= 2.63±0.21) [P
 
Date 2020-11-03T06:29:21Z
2020-11-03T06:29:21Z
2020-09
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/55605
 
Language en_US
 
Relation Int. cl. (2015.01)- A61K 36/00, A61K 36/75, A61K 127/00, A61P 39/00, A61P 39/06
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJNPR Vol.11(3) [September 2020]