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Biopotentials of secondary metabolites isolated from marine sponges

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Relation http://eprints.cmfri.org.in/6246/
 
Title Biopotentials of secondary metabolites isolated from marine sponges
 
Creator Joseph, Selvin
Lipton, A P
 
Subject Sponges
Biochemical composition
 
Description The secondary metabolites of three sponges collected as bycatch in the fishing nets were explored for biological
potencies. The sponge Dendrilla nigra exhibited wider biological activity. It showed potent activity in antibacterial,
brineshrimp cytotoxicity, larvicidal, antifouling and ichthyotoxic assays. One of the well-studied cytotoxic
sponge Axinellu donnani was least active in brineshrimp cytotoxicity assay. The secondary metabolites of Clathria
gorgonoides were highly cytotoxic albeit it showed least activity in other bioassays. Based on the present findings,
it could be inferred that the bioassay-guided fractionation and purification of D. nigra may come up with potent
bioactive drugs
 
Date 2004
 
Type Article
PeerReviewed
 
Format application/pdf
 
Language en
 
Identifier http://eprints.cmfri.org.in/6246/1/620.pdf
Joseph, Selvin and Lipton, A P (2004) Biopotentials of secondary metabolites isolated from marine sponges. Hydrobiologia, 513. pp. 231-238.