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Synthesis of pyrazines and imidazoles using lemon juice (Citrus limon) as a recyclable catalyst

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Field Value
 
Title Synthesis of pyrazines and imidazoles using lemon juice (Citrus limon) as a recyclable catalyst
 
Creator Kawle, Pravin
Kamble, Kapil
 
Subject Green synthesis
Pyrazines
Imidazoles
Natural acid catalyst
Recyclable catalyst
 
Description 1887-1892
One-pot four component synthesis of 2,5,6-triaryl pyrazines, 1,2,4,5-tetraaryl imidazoles and 2,2,4,5-tetraaryl imidazoles have been achieved from benzoin, aryl amine, ammonium acetate and aryl ketone /aryl aldehydes using lemon juice (Citrus limon) as an ecofriendly catalyst in good yield under mild conditions. The antibacterial action exhibited by the synthesized compounds against clinical isolates obtained from urinary tract catheters of infected patients is close to the standard drug tetracycline. Recovery of lemon juice after completion of reaction eliminates the need to handle side products, making this process more safe and user friendly.
 
Date 2020-12-08T05:27:05Z
2020-12-08T05:27:05Z
2020-12
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55772
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.59B(12) December 2020]