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New insights on the antifungal activity of essential oil of Salvia desoleana Atzei et Picci, an endemic plant from folk medicine of Sardinia, Italy

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Title New insights on the antifungal activity of essential oil of Salvia desoleana Atzei et Picci, an endemic plant from folk medicine of Sardinia, Italy
 
Creator Maxia, A
Piras, A
Falconieri, D
Maccioni, D
Porcedda, S
Gonçalves, M J
Cavaleiro, C
Salgueiro, L
 
Subject Antifungal activity
Ethnomedicine
Essential oil
Germ tube
Salvia desoleana
 
Description 757-760
This work reports the results concerning the antifungal activity of the essential oil obtained from Salvia desoleana, an endemic plant from folk medicine of Sardinia Island, Italy. Chemical analysis of S. desoleana essential oil isolated by hydrodistillation was carried out by gas chromatography (GC-FID) and gas chromatography–mass spectrometry (GC-MS). The essential oil contains high amounts of oxygenated monoterpenes and sesquiterpene hydrocarbons, being linalyl acetate (21.0%), a-terpinyl acetate (17.3%), 1,8-cineole (6.7%), linalool (3.6%), sclareol (3.5%) and germacrene D (22.1%) the main compounds. The oil was more active against the yeast Cryptococcus neoformans and the dermatophyte Trichophyton rubrum with MIC values of 0.16 μL/mL and 0.32 μL/mL, respectively. The oil revealed an important inhibitory effect on the germ tube formation in C. albicans. It was able to achieve about 40% of inhibition of filamentation at concentrations as low as 0.08 µL/mL. These findings add significant information to the biological activity of the essential oil of S. desoleana, specifically to its antifungal properties, thus justifying and reinforcing the use of this plant in traditional medicine.
 
Date 2020-12-23T10:01:56Z
2020-12-23T10:01:56Z
2020-10
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/55828
 
Language en_US
 
Relation Int. Cl.20: C23C 18/30,  A61K 36/00, C11B 9/00, F24H 3/08, A01N 1/00
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJTK Vol.19(4) [October 2020]