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<p>An investigation of traditional uses and anti-inflammatory property of <em>Clematis buchananiana</em> De Candolle and<em> Tupistra nutans</em> Wall. ex Lindl.: Native ethnomedicinal plants from Sikkim, India</p>

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Title Statement <p>An investigation of traditional uses and anti-inflammatory property of <em>Clematis buchananiana</em> De Candolle and<em> Tupistra nutans</em> Wall. ex Lindl.: Native ethnomedicinal plants from Sikkim, India</p>
 
Added Entry - Uncontrolled Name Singh, B ; Department of Zoology, School of Life Sciences, Sikkim University, Gangtok, Sikkim, India
Brahma, M ; Department of Zoology, School of Life Sciences, Sikkim University, Gangtok, Sikkim, India
Gurung, J ; Department of Zoology, School of Life Sciences, Sikkim University, Gangtok, Sikkim, India
 
Uncontrolled Index Term Clematis buchananiana; Ethnomedicine; Inflammation; Sikkim; Tupistra nutans
 
Summary, etc. <p>In the traditional medicinal system of Sikkim <em>Clematis buchananiana</em> and <em>Tupistra nutans</em> is used extensively to treat various ailments, however, they have not been validated for their anti-inflammatory property by <em>in vitro</em> method. Therefore, the present study was carried out to investigate specific ethnomedicinal uses, <em>in-vitro</em> anti-inflammatory property, and phytochemical constituents of <em>Clematis buchananiana</em> and <em>Tupistra nutans</em>. The ethnomedicinal usage was studied by calculating the value for fidelity level, use-value, and informant consensus factor. Stabilization of human red blood cell membrane and protein denaturation method was used to study anti-inflammatory property. The phytochemicals were analysed by the methods described elsewhere. <em>Clematis buchananiana</em> was found to be used more frequently for sinusitis, headache, cold and <em>Tupistra nutans</em> for high blood pressure, diabetes and stomach-ache. Both <em>C. buchananiana</em> and <em>T. nutans</em> was found to inhibit the HRBC membrane and protein denaturation effectively in a dose-dependent manner. However, inhibition of haemolysis and protein denaturation by <em>C. buchananiana</em> was found to be higher than <em>T. nutans</em> at all doses. The phytochemical screening revealed the presence of <br /> anti-inflammatory metabolites such as flavonoids and phenolics in both the plants. The results provide evidence for the anti-inflammatory property of<em> C. buchananiana</em> and <em>T. nutans</em>.</p> <p><strong><br /></strong><em> </em></p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2020-12-30 12:30:42
 
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http://op.niscair.res.in/index.php/IJTK/article/view/44514
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 19, ##issue.no## 4 (2020): Indian Journal of Traditional Knowledge
 
Language Note en