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New insights on the antifungal activity of essential oil of <em>Salvia desoleana</em> Atzei et Picci, an endemic plant from folk medicine of Sardinia, Italy

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Title Statement New insights on the antifungal activity of essential oil of <em>Salvia desoleana</em> Atzei et Picci, an endemic plant from folk medicine of Sardinia, Italy
 
Added Entry - Uncontrolled Name Piras, A ; Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, SP 8, Monserrato – Sestu km 0.700, 09042 Monserrato (CA), Italy
Maxia, A ; Department of Life and Environmental Sciences, Botany section, University of Cagliari, Viale Sant’Ignazio da Laconi 13, 09123 Cagliari, Italy
Falconieri, D ; State Institute of Higher Education “Michele Giua”, via Montecassino, 09134 Cagliari, Italy
Maccioni, D ; Department of Life and Environmental Sciences, Botany section, University of Cagliari, Viale Sant’Ignazio da Laconi 13, 09123 Cagliari, Italy
Porcedda, S ; Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, SP 8, Monserrato – Sestu km 0.700, 09042 Monserrato (CA), Italy
Gonçalves, M J; Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, SP 8, Monserrato – Sestu km 0.700, 09042 Monserrato (CA), Italy
Cavaleiro, C ; University of Coimbra Faculty of Pharmacy, Azingha de Santa Comba, 3000-548 Coimbra Portugal
Salgueiro, L ; University of Coimbra Faculty of Pharmacy, Azingha de Santa Comba, 3000-548 Coimbra Portugal
 
Uncontrolled Index Term Antifungal activity; Ethnomedicine; Essential oil; Germ tube; Salvia desoleana
 
Summary, etc. <p>This work reports the results concerning the antifungal activity of the essential oil obtained from <em>Salvia desoleana</em>, an endemic plant from folk medicine of Sardinia Island, Italy. Chemical analysis of <em>S. desoleana</em> essential oil isolated by hydrodistillation was carried out by gas chromatography (GC-FID) and gas chromatography–mass spectrometry (GC-MS). The essential oil contains high amounts of oxygenated monoterpenes and sesquiterpene hydrocarbons, being linalyl acetate (21.0%), a-terpinyl acetate (17.3%), 1,8-cineole (6.7%), linalool (3.6%), sclareol (3.5%) and germacrene D (22.1%) the main compounds. The oil was more active against the yeast <em>Cryptococcus neoformans</em> and the dermatophyte <em>Trichophyton rubrum</em> with MIC values of 0.16 μL/mL and 0.32 μL/mL, respectively. The oil revealed an important inhibitory effect on the germ tube formation in <em>C. albicans.</em> It was able to achieve about 40% of inhibition of filamentation at concentrations as low as 0.08 µL/mL. These findings add significant information to the biological activity of the essential oil of <em>S. desoleana</em>, specifically to its antifungal properties, thus justifying and reinforcing the use of this plant in traditional medicine.</p> <p><strong><br /></strong><em> </em></p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2020-12-30 12:30:42
 
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http://op.niscair.res.in/index.php/IJTK/article/view/44509
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 19, ##issue.no## 4 (2020): Indian Journal of Traditional Knowledge
 
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