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A convenient synthesis and biological activities of N-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
A convenient synthesis and biological activities of N-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides
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| Creator |
Anusha, D
Praveena, G Zehra, A Tiwari, A K Prakasham, R S Raju, B China |
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| Subject |
N'-Pyridinylmethylenebenzohydrazides
Nicotinaldehydes Benzohydrazides Anti-microbial activity Anti-hyperglycemic activity |
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| Description |
117-126
Series of N'-(pyridine-3-ylmethylene)benzohydrazides 3a-y have been prepared by the condensation of nicotinaldehydes 1a-e with benzohydrazides 2a-e in the presence of glacial AcOH in ethanol at room temperature. Total twenty five compounds have been prepared and confirmed based on spectral data. The compounds have been evaluated for anti-microbial, free radical scavenging (DPPH, ABTS.+) and α-glucosidase inhibitory activities. Compound 3h has shown potent anti-fungal activity. Compounds 3f-g and 3j have shown potent ABTS.+ free radical scavenging activity. Compound 3d has shown potent anti-hyperglycemic activity. |
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| Date |
2021-01-12T07:01:53Z
2021-01-12T07:01:53Z 2021-01 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/55919 |
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| Language |
en_US
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| Rights |
 CC Attribution-Noncommercial-No Derivative Works 2.5 India
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.60B(01) [January 2021]
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