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<p>Synthesis and characterization of a new water-soluble non-cytotoxic mito-tracker capped silicon quantum dot</p>

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Title Statement <p>Synthesis and characterization of a new water-soluble non-cytotoxic mito-tracker capped silicon quantum dot</p>
 
Added Entry - Uncontrolled Name Saha, Subrata Kumar; Department of Physics, Sambhu Nath College, Labpur, Birbhum 731 303, West Bengal, India
Saha, Swadhin Kumar; Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713 104, West Bengal, India
Dhara, Koushik ; Department of Chemistry, Sambhu Nath College, Labpur, Birbhum 731 303, West Bengal, India
Chattopadhyay, Pabitra ; Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713 104, West Bengal, India
Sarkar, Arnab ; Department of Chemistry, The University of Burdwan, Golapbag, Burdwan 713 104, West Bengal, India
DST, New Delhi (Project No. SB/FT/CS-142/2012);Department of Higher Education, Science & Technology and Biotechnology (Science & Technology Branch), Govt. of West Bengal (Project No. 698 (Sanc.)/ST/P/S & T/15-G/2015)
 
Uncontrolled Index Term Solid state chemistry; Silicon quantum dots
Silicon quantum dots, Fluorescence, XPS, Cytotoxicity, Mitochondrial target
 
Summary, etc. <p style="text-align: justify;">Allyl triphenylphosphonium bromide based mito-tracker capped silicon quantum dot (<strong>Mito-SiQDs</strong>) has been synthesized through an inverse micelle process. It was then fully characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, dynamic light scattering techniques and X-ray photoelectron spectroscopic method. Energy dispersive X-ray spectroscopy analyses of the quantum dots confirm the presence of carbon, silicon, phosphorous and bromine atoms in <strong>Mito-SiQDs</strong>. Morphological study by transmission electron microscopy experiment showed the formation of the particles of size 11-12 nm of quantum dot dimension. The high negative zeta potential value of –23.7 mV calculated from dynamic light scattering study indicates the high stability of the circumvent agglomeration of <strong>Mito-SiQDs</strong>. The mito-tracker capped silicon quantum dot has blue emission at 400 nm wavelength upon excitation at 327 nm. <strong>Mito-SiQDs</strong> has not shown any significant cytotoxic effect with 10 to 50 μL/mL concentration on HeLa cell line for at least up to 12 h of its treatment. The <strong>ito</strong>- <strong>iQDs </strong>would be useful a possible fluorescent marker to visualize mitochondrial subcellular compartment in living cell through fluorescence imaging study.</p><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section A (IJCA)
2021-01-18 15:11:33
 
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http://op.niscair.res.in/index.php/IJCA/article/view/38694
 
Data Source Entry Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 60, ##issue.no## 1 (2021): INDIAN JOURNAL OF CHEMISTRY- SECTION A
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCA/article/download/38694/465520526
http://op.niscair.res.in/index.php/IJCA/article/download/38694/465520529
 
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