Record Details

<p>Free radical scavenging and α-glucosidase inhibitory activity of (<em>E</em>)-methyl/ethyl-3-(2-hydroxyphenyl)acrylates</p><p> </p>

Online Publishing @ NISCAIR

View Archive Info
 
 
Field Value
 
Authentication Code dc
 
Title Statement <p>Free radical scavenging and α-glucosidase inhibitory activity of (<em>E</em>)-methyl/ethyl-3-(2-hydroxyphenyl)acrylates</p><p> </p>
 
Added Entry - Uncontrolled Name Bhimapaka, China Raju
Hariprasad, K Siva ; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Harikrishna, G ; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Tiwari, A K ; Centre for Natural Products & Traditional Knowledge CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Zehra, A ; Centre for Natural Products & Traditional Knowledge CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
 
Uncontrolled Index Term (E)-Methyl/ethyl-3-(2-hydroxyphenyl)acrylates, salicylaldehydes, free radical scavenging, α-glucosidase inhibitory activity
 
Summary, etc. <p class="Abstract">(<em>E</em>)-Methyl/ethyl-3-(2-hydroxyphenyl)acrylates <strong>3a-x</strong> have been prepared by the reaction of salicylaldehydes <strong>1a-l</strong> with Wittig reagents such as methyl (triphenylphosphoranylidene)acetate <strong>2a</strong> and ethyl (triphenylphosphoranylidene)acetate <strong>2b</strong> in dry DCM at room temperature. All the synthesized compounds have been evaluated for free-radical scavenging and α-glucosidase inhibitory activities. Compounds <strong>3c </strong>and<strong> 3d </strong>display DPPH free radical scavenging activity. All the compounds have shown ABTS free radical scavenging activity except four compounds <strong>3s-t</strong> and <strong>3w-x</strong>. Compounds <strong>3g</strong>, <strong>3p </strong>and <strong>3r</strong> display α-glucosidase inhibitory activity.</p><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-01-20 16:29:04
 
Electronic Location and Access application/pdf
http://op.niscair.res.in/index.php/IJCB/article/view/40509
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 01 (2021): Indian Journal of Chemistry Section - B (IJCB)
 
Language Note en
 
Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/40509/465526374
http://op.niscair.res.in/index.php/IJCB/article/download/40509/465526721
 
Terms Governing Use and Reproduction Note Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India© 2015. The Council of Scientific &amp; Industrial Research, New Delhi.