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<p>A convenient synthesis and biological activities of <em>N</em>-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides</p><p> </p>

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Title Statement <p>A convenient synthesis and biological activities of <em>N</em>-(pyridin-3-ylmethylene) benzohydrazides by the condensation of nicotinaldehydes with benzohydrazides</p><p> </p>
 
Added Entry - Uncontrolled Name Bhimapaka, China Raju ; CSIR-Indian Institute of Chemical Technology Hyderabad, Telangana, India
Anusha, D ; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Praveena, G ; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Prakasham, R S ; Department of Organic Synthesis & Process Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Zehra, A ; Centre for Natural Products & Traditional Knowledge CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
Tiwari, A K ; Centre for Natural Products & Traditional Knowledge CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India
 
Uncontrolled Index Term N'-Pyridinylmethylenebenzohydrazides, nicotinaldehydes, benzohydrazides, anti-microbial activity, anti-hyperglycemic activity
 
Summary, etc. <p>Series of <em>N</em>'-(pyridine-3-ylmethylene)benzohydrazides <strong>3a-y</strong> have been prepared by the condensation of nicotinaldehydes <strong>1a-e</strong> with benzohydrazides <strong>2a-e</strong> in the presence of glacial AcOH in ethanol at room temperature. Total twenty five compounds have been prepared and confirmed based on spectral data. The compounds have been evaluated for anti-microbial, free radical scavenging (DPPH, ABTS<sup>.+</sup>) and α-glucosidase inhibitory activities. Compound <strong>3h</strong> has shown potent anti-fungal activity. Compounds <strong>3f-g</strong> and <strong>3j</strong> have shown potent ABTS<sup>.+</sup> free radical scavenging activity. Compound <strong>3d</strong> has shown potent anti-hyperglycemic activity.</p><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-01-20 16:29:04
 
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http://op.niscair.res.in/index.php/IJCB/article/view/40586
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 01 (2021): Indian Journal of Chemistry Section - B (IJCB)
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/40586/465526742
http://op.niscair.res.in/index.php/IJCB/article/download/40586/465526743
 
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