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<strong><span lang="EN-GB">Protective role of <em>Ipomoea aquatica</em> Forsk. crude extract on rat tissues in the presence of acephate and carbofuran by histopathology and cytometric determination</span></strong>

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Title Statement <strong><span lang="EN-GB">Protective role of <em>Ipomoea aquatica</em> Forsk. crude extract on rat tissues in the presence of acephate and carbofuran by histopathology and cytometric determination</span></strong>
 
Added Entry - Uncontrolled Name Datta, Sanjukta
Manna, Krishnendu
Dey, Sanjit
Dhar, Pubali
Ghosh, Mahua
 
Uncontrolled Index Term Flowcytometry, MnSOD, NF-E2-related factor-2, Nrf-2-ARE pathway, Pesticide toxicity, Water spinach
 
Summary, etc. <p style="text-align: justify;"><em>Ipomoea aquatica</em> Forsk., commonly called water spinach ( ‘<em>kalmi</em>’ in Bengali)<em> </em>is an underexploited local green leafy vegetable having enormous scope as a cheap antioxidant source. The study explores the ameliorative effect of aqueous <em>I. aquatica</em> extract (IAE) in acephate and carbofuran treated Wistar male rats. Aqueous IAE (@ 20 mg/kg body wt.), administered to rats treated with organophosphate acephate (@ 30 mg/kg body wt.) and carbamate carbofuran (@ 0.1 mg /kg body wt.), attenuated the cholinesterase activity in brain, liver and cellular blood and reformed the histological perturbations in the brain cortex as well as the kidney anomalies, to a good extent. The IAE also upregulated the NF-E2-related factor-2 (Nrf-2) and MnSOD gene expression against pesticide toxicity. Hence, results of the present study intervenes into a new approach of justifying the deleterious side effects of pesticides that are commonly used, and how green leafy vegetables can help ameliorate those harmful effects.</p>
 
Publication, Distribution, Etc. Indian Journal of Experimental Biology (IJEB)
2021-02-01 10:54:30
 
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http://op.niscair.res.in/index.php/IJEB/article/view/45724
 
Data Source Entry Indian Journal of Experimental Biology (IJEB); ##issue.vol## 59, ##issue.no## 02 (2021): IJEB [February 2021]
 
Language Note en