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Bioprospecting of the underutilized endemic taxon Cissus woodrowii (Stapf ex Cooke) Santapau for its antioxidant activity and phenolic profiling

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Title Bioprospecting of the underutilized endemic taxon Cissus woodrowii (Stapf ex Cooke) Santapau for its antioxidant activity and phenolic profiling
 
Creator Kolap, Rupali Mukesh
Gulave, Akshay Bharat
Zimare, Saurabha Bhimrao
 
Subject Antioxidant activity
Cissus woodrowii
HPLC
LC-HRMS
Phenolic profiling
Woodrow’s grape tree
 
Description 250-259
The present study explored the antioxidant potential of endemic Cissus woodrowii (CW) which is an underutilised tree taxon of the Vitaceae family. Maximum per cent yield (13.49%), total phenolic content (24.14 mg TAE/g dry weight), and total flavonoid content (18.45 mg QE/g dry weight) were recorded in the methanolic leaf extract. Whereas the in vitro antioxidant activities of different extracts were assessed using 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), 2,2-diphenyl-1-picrylhydrazyl, hydroxyl, nitric oxide, hydrogen peroxide percent radical scavenging activity (% RSA), antioxidant power assay (ferric-reducing antioxidant power), and total antioxidant capacity (phosphomolybdate assay). Antioxidant activity of CW extract may be due to its high level of phenolic compounds, which were screened through liquid chromatography–high-resolution mass spectrometry (LC-HRMS), and the selected three phenolic compounds were quantified using high-performance liquid chromatography (HPLC). The HPLC analysis revealed a higher concentration of gallic acid (119.78 µg/g dry weight), followed by quercetin (22.13 µg/g dry weight) and embelin (21.09 µg/g dry weight). This is the first report on this underexplored taxon which could be employed for the development of several nutraceuticals and pharmaceuticals.
 
Date 2021-02-04T09:23:42Z
2021-02-04T09:23:42Z
2020-12
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/56147
 
Language en_US
 
Relation Int. cl. (2015.01)− A61K 36/00, A61K 36/87, A61K 127/00, A61P 39/00
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJNPR Vol.11(4) [December 2020]