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<p style="text-align: justify;">Antioxidant and antitubercular activities of leaf extracts of <em>Canthium dicoccum </em>(Gaertn.) and <em>Amischophacelus axillaris </em>(L.)</p>

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Title Statement <p style="text-align: justify;">Antioxidant and antitubercular activities of leaf extracts of <em>Canthium dicoccum </em>(Gaertn.) and <em>Amischophacelus axillaris </em>(L.)</p>
 
Added Entry - Uncontrolled Name Meghashree, K. S. ; Department of PG Studies and Research in Chemistry, Sahyadri Science College, Shivamogga 577203, Karnataka, India
Latha, K. P. ; Department of PG Studies and Research in Chemistry, Sahyadri Science College, Shivamogga 577203, Karnataka, India
Vagdevi, H. M. ; Department of PG Studies and Research in Chemistry, Sahyadri Science College, Shivamogga 577203, Karnataka, India
 
Uncontrolled Index Term plant extraction
Amischophacelus axillaris (L.); Antioxidant, Antitubercular; Canthium dicoccum (Gaertn.); Ethanol extract; Ethyl acetate extract.
 
Summary, etc. <p style="text-align: justify;">Modern civilization is facing hundreds of disorders associated with free radicals. The natural antioxidants from non-edible plants are gaining importance to fight against these disorders. One such commonly seen disorder is tuberculosis, which is responsible for about 8 million deaths annually worldwide. This study intends to evaluate the ethanol extracts of <em>Canthium dicoccum </em>(Gaertn.) and ethyl acetate extracts of <em>Amischophacelus axillaris </em>(L.)<em> </em>for antioxidant and antitubercular activities. The antioxidant activity of the extracts has been evaluated using DPPH radical scavenging methods. The results of the study indicated that ethanol extract of <em>C. dicoccum </em>(Gaertn.) and ethyl acetate extract of <em>A. axillaris</em> (L.)<em> </em>possess promising DPPH radical scavenging activity. The antitubercular activity of ethanol extract of <em>C. dicoccum </em>(Gaertn.) and ethyl acetate extract of<em> A. axillaris </em>(L.)<em> </em>have been evaluated against <em>Mycobacterium tuberculosis</em> H73Rv strain using Microplate Alamar Blue Assay (MABA). The activity was documented within the MIC range of 0.8 to 12.5 µg/mL for <em>C. dicoccum </em>(Gaertn.) and 0.8 to 50 µg/mL for <em>A. axillaris </em>(L.). The results of MABA showed that both the plant extracts exhibited excellent antitubercular activity. The present investigation suggests that <em>C. dicoccum </em>(Gaertn.) and <em>A. axillaris </em>(L.)<em> </em>possess remarkable antioxidant and antitubercular activity.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2021-02-08 15:23:32
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/30454
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 11, ##issue.no## 4 (2020): December 2020
 
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