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2-Pyridone quinoline hybrids as potent antibacterial and antifungal agents
NOPR - NISCAIR Online Periodicals Repository
View Archive Info| Field | Value | |
| Title |
2-Pyridone quinoline hybrids as potent antibacterial and antifungal agents
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| Creator |
Desai, N C
Harsora, J P Mehta, H K |
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| Subject |
Quinoline
2-pyridone Antimicrobial Structure activity relationship |
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| Description |
261-266
An efficient synthetic strategy for the synthesis of 6-amino-1-(((2-chloroquinolin-3-yl)methylene)amino)-2-oxo-4-(aryl)-1,2-dihydropyridine-3,5-dicarbonitriles is well described in this paper. Structures of synthesized compounds have been identified by standard spectroscopic techniques like 1H NMR, 13C NMR, IR and mass spectroscopy. Results of the biological activity reveals that electron withdrawing groups and presence of –OH group on meta position play a significant role for the increment in the antibacterial and antifungal activities respectively of 3a-j. In the present study, it has been observed that compounds 3i and 3e are the most active antimicrobials. |
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| Date |
2021-02-11T10:33:08Z
2021-02-11T10:33:08Z 2021-02 |
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| Type |
Article
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| Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/56215 |
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| Language |
en_US
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| Rights |
 CC Attribution-Noncommercial-No Derivative Works 2.5 India
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| Publisher |
NISCAIR-CSIR, India
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| Source |
IJC-B Vol.60B(02) [February 2021]
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