Record Details

<p>2-Pyridone quinoline hybrids as potent antibacterial and antifungal agents</p><p> </p>

Online Publishing @ NISCAIR

View Archive Info
 
 
Field Value
 
Authentication Code dc
 
Title Statement <p>2-Pyridone quinoline hybrids as potent antibacterial and antifungal agents</p><p> </p>
 
Added Entry - Uncontrolled Name Desai, Nisheeth C; Maharaja Krishnakumarsinhji Bhavnagar University
Mehta, H K ; Division of Medicinal Chemistry, Department of Chemistry (DST-FIST Sponsored & UGC NON-SAP), Mahatma Gandhi Campus, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar 364 002, India
Harsora, J P ; Shri M. P. Shah Arts and Science College, Surendranagar 363 001, India
 
Uncontrolled Index Term Quinoline, 2-pyridone,antimicrobial,structure activity relationship
 
Summary, etc. <p>An efficient synthetic strategy for the synthesis of 6-amino-1-(((2-chloroquinolin-3-yl)methylene)amino)-2-oxo-4-(aryl)-1,2-dihydropyridine-3,5-dicarbonitriles is well described in this paper. Structures of synthesized compounds have been identified by standard spectroscopic techniques like <sup>1</sup>H NMR, <sup>13</sup>C NMR, IR and mass spectroscopy. Results of the biological activity reveals that electron withdrawing groups and presence of –OH group on <em>meta</em> position play a significant role for the increment in the antibacterial and antifungal activities respectively of <strong>3a-j</strong>. In the present study, it has been observed that compounds <strong>3i</strong> and <strong>3e</strong> are the most active antimicrobials.</p><p> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-02-15 15:57:41
 
Electronic Location and Access application/pdf
application/pdf
http://op.niscair.res.in/index.php/IJCB/article/view/35076
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 2 (2021): Indian Journal of Chemistry Section - B (IJCB)
 
Language Note en
 
Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/35076/0
http://op.niscair.res.in/index.php/IJCB/article/download/35076/465508468
http://op.niscair.res.in/index.php/IJCB/article/download/35076/465510752
http://op.niscair.res.in/index.php/IJCB/article/download/35076/465510754
http://op.niscair.res.in/index.php/IJCB/article/download/35076/465510755
 
Terms Governing Use and Reproduction Note Except where otherwise noted, the Articles on this site are licensed under Creative Commons License: CC Attribution-Noncommercial-No Derivative Works 2.5 India© 2015. The Council of Scientific &amp; Industrial Research, New Delhi.