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<p>Cadmium induced oxidative stress-mediated pathophysiological alterations in chickens and their amelioration by polyherbal mixture enriched feed <strong></strong></p>

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Title Statement <p>Cadmium induced oxidative stress-mediated pathophysiological alterations in chickens and their amelioration by polyherbal mixture enriched feed <strong></strong></p>
 
Added Entry - Uncontrolled Name Patel, Urvesh D; Junagadh Agricultural University
Bhatt, P R; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Junagadh Agricultural University, Junagadh 362 001, Gujarat, India
Pandya, K B; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Junagadh Agricultural University, Junagadh 362 001, Gujarat, India
Patel, H B; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Junagadh Agricultural University, Junagadh 362 001, Gujarat, India
Modi, C M; Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and Animal Husbandry, Junagadh Agricultural University, Junagadh 362 001, Gujarat, India
 
Uncontrolled Index Term Broiler chickens, Cadmium toxicity, LC-QToF-MS analysis, Polyherbal mixture enriched feed, Scanning electron microscopy
 
Summary, etc. The study was conducted to evaluate sub-acute toxicity of cadmium (Cd) in broiler chickens and its amelioration by polyherbal mixture enriched feed (PHMEF). Thirty broiler chickens were divided into five groups. Chickens of group 1 were kept as control (C1). Chickens of group T1, T2, T3 and T4 were exposed to cadmium (as cadmium chloride) through drinking water (100 ppm), Vitamin C with Vitamin E (250 mg/kg each) in feed + Cd in drinking water (100 ppm), PHMEF (2%) alone, and PHMEF (2%) + cadmium in drinking water (100 ppm) for 28 days, respectively. Haematology, serum biochemical parameters, oxidative stress parameters like superoxide dismutase, catalase, reduced-glutathione and malondialdehyde, cadmium accumulation in organs like kidney, liver and thigh muscle, scanning electron microscopy (SEM) of ileum, and histopathological examination of kidney, liver and intestine were performed to evaluate toxicity of cadmium and ameliorating potential of PHMEF in broiler chickens. PHMEF modifies biochemical parameters, and oxidative stress markers. There was a significant reduction of cadmium accumulations in the PHMEF treated group.<br />Polyherbal mixture enriched feed showed ameliorating effect against cadmium induced toxicity due to antioxidant effect as well as effect on accumulation of the cadmium in chickens
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2021-03-03 16:09:58
 
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http://op.niscair.res.in/index.php/IJTK/article/view/25545
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 20, ##issue.no## 1 (2021): Indian Journal of Traditional Knowledge
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJTK/article/download/25545/465479577