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<p>Synthesis and biological evaluation of novel 3-aryl-4-methoxy <em>N</em>-alkyl maleimides</p><p> </p>

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Title Statement <p>Synthesis and biological evaluation of novel 3-aryl-4-methoxy <em>N</em>-alkyl maleimides</p><p> </p>
 
Added Entry - Uncontrolled Name Gosavi, Kirankumar S.; Department of Chemistry, KVPS’s Kisan Arts, Commerce and Science College, Parola 425 111, India (Affiliated to KBC North Maharashtra University, Jalgaon
Mahale, Keshao A.; Organic Chemistry Research Centre, Department of Chemistry, KRT. Arts, BH Commerce and AM Science College, Gangapur Road, Nashik 422 002, India
Patil, Nilesh S.; Department of Chemistry, RD and SH National College and SWA Science College, Linking Road, Bandra (West), Mumbai 400 050, India
Patil, Sambhaji V; MVP Samaj’s Arts, Science and Commerce College, Ozar, Nashik 422 206, India
University Grants Commission, New Delhi.
 
Uncontrolled Index Term Maleimide, maleic anhydride, MIC, antifungal, antibacterial 
 
Summary, etc. <p>In the present investigation, a series of 3-aryl-4-methoxy <em>N</em>-alkyl maleimide<strong> 5a-l</strong> have been synthesized and screened for their antimicrobial activity against one Gram positive bacteria (<em>S. aureus</em>), one Gram negative bacteria (<em>E. coli</em>) and fungal strains (<em>C. albicans</em>, <em>C. tropicalis</em>,  <em>A. niger</em> and <em>A. clavatus</em>). The structures of the compounds have been substantiated by their IR, NMR, mass and elemental analysis. The minimum inhibitory concentrations (MICs) of synthesized maleimides have been determined by broth microdilution method. Of the newly synthesized maleimides, compounds <strong>5c</strong>, <strong>5f</strong>, <strong>5h</strong>, <strong>5i</strong>, <strong>5k</strong> and <strong>5l</strong> registered significant activity against the tested microorganisms.</p><p style="text-align: justify;"> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-03-16 16:32:53
 
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http://op.niscair.res.in/index.php/IJCB/article/view/41338
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 3 (2021): Indian Journal of Chemistry- Section-B, (IJCB)
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/41338/465531452
http://op.niscair.res.in/index.php/IJCB/article/download/41338/465531454
 
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