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<p style="text-align: justify;">Free radical scavenging and elastase inhibitory activity of different extracts of <em>Leucas aspera </em>(Willd.) Link-<em> </em>An<em> in vitro </em>study</p>
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dc |
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| Title Statement |
<p style="text-align: justify;">Free radical scavenging and elastase inhibitory activity of different extracts of <em>Leucas aspera </em>(Willd.) Link-<em> </em>An<em> in vitro </em>study</p> |
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Gangadharan, Asha ; Department of Biochemistry, Mar Athanasius College, Kothamangalam, Eranakulam Dist, Kerala 686691, India J, Benny P; Department of Chemistry, St.Thomas College, Pala, Kottayam Dist. Kerala 686574, India CSIR-UGC, India |
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medicinal plant Biochemistry,Phytochemistry,Enzymology, Anti-elastase activity; Antioxidant activity; Leucas aspera (Willd.) Link; Phytochemical analysis. |
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| Summary, etc. |
<p style="text-align: justify;"><em>Leucas aspera </em>(Willd.) Link has been used for curing various ailments including skin disease in traditional medicine for decades. The aim of the study was to evaluate the <em>in vitro</em> antioxidant potential and anti-elastase activity of<em> L. aspera </em>(Willd.) Link. The hexane, ethyl acetate, acetone and ethanol extracts were prepared using the Soxhlet extraction method. The phytochemical analysis, <em>in vitro </em>free radical scavenging, and anti-elastase activities, were conducted. The total phenol and flavonoids compounds were found to be significantly high for the hexane extract and the ethyl acetate extract respectively<em>.</em> <em>In vitro</em> antioxidant assays like percentage reducing power, DPPH radical scavenging activity, the total antioxidant capacity by FRAP assay, revealed that the acetone extract of the plant <em>L. aspera </em>possesses significantly the highest activity. The anti elastase assay revealed that all the extracts possess elastase inhibitory activity and the hexane extract possessed significantly highest activity with IC<sub>50</sub> of 247.42 µg/mL, at a significant level (α) <span style="text-decoration: underline;"><</span>0.05. The present result supports the traditional use of <em>L. aspera</em>.</p> |
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| Publication, Distribution, Etc. |
Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)] 2021-04-09 16:24:48 |
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| Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJNPR/article/view/17096 |
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Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 1 (2021): March 2021 |
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| Language Note |
en |
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| Nonspecific Relationship Entry |
http://op.niscair.res.in/index.php/IJNPR/article/download/17096/465542573 http://op.niscair.res.in/index.php/IJNPR/article/download/17096/465542575 http://op.niscair.res.in/index.php/IJNPR/article/download/17096/465542576 http://op.niscair.res.in/index.php/IJNPR/article/download/17096/465548148 |
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