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Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives

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Title Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives
 
Creator Dayananda, P
Nayak, Janardhana
D’Souza, Vineetha Telma
 
Subject Quinoline
Thiadiazole
Thiourea
Antibacterial
Antifungal
 
Description 633-638
A novel series of 1-[(substituted 2-chloroquinolin-3-yl)methylidene]-3-[substituted-5-phenyl-1,3,4-thiadiazol-2-yl] thioureas have been synthesized by acid catalyzed reaction between the 1-(5-substitued phenyl-1,3,4-thiadiazol-2-yl) thioureas and 6-substituted-2-chloro-3-formyl quinolines. The structures of these compounds have been confirmed by spectral techniques like IR, 1H NMR and mass spectroscopy. The new compounds have been screened for their antibacterial and antifungal activity studies. Most of the compounds show good activity comparable with that of the standard drugs.
 
Date 2021-04-15T04:45:35Z
2021-04-15T04:45:35Z
2021-04
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/57099
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.60B(04) [April 2021]