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<p>Experimental study on antiepileptic action of <em>Kousheyashma Bhasma</em></p>

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Title Statement <p>Experimental study on antiepileptic action of <em>Kousheyashma Bhasma</em></p>
 
Added Entry - Uncontrolled Name M, NIDHIN M; PG SCHOLAR ,DEPARTMENT OF RASASHASTRA & BHAISHAJYA KALPANA SREE DHARMASTHALA MANJUNATHESHWARA AYURVEDA COLLEGE & HOSPITAL
Sharma, Govinda K; PROFESSOR ,DEPARTMENT OF RASASHASTRA & BHAISHAJYA KALPANA SREE DHARMASTHALA MANJUNATHESHWARA AYURVEDA COLLEGE & HOSPITAL
Bhat, Sudhakar ; Research officer, Department of Pharmacology and Toxicology SDM Centre for Research in Ayurveda and Allied Sciences, Udupi
G, Chaitra G; PG scholar, Department of manasa roga, Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan Karnataka
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Uncontrolled Index Term Antiepilectic activity, Epilepsy, Kousheyashma Bhasma
 
Summary, etc. Epilepsy is one of the most common neurological diseases. It is characterized by recurrent episodes of disturbance in movement, sensation and consciousness. With increased incidence rate of epilepsy, numbers of treatment modalities as well as formulations are being developed in recent years. In Ayurveda also many formulations are available for treatment of epilepsy. However, there is a search of formulations which can show quick and longstanding efficacy on epilepsy. <p><em>Kousheyashma </em>is a mineral drug used in Ayurveda pharmaceutics. It is yellowish white and is identified as asbestos. Magnesium calcium and silicate are chief chemical entity of this drug. It is an easily and abundantly available mineral in India. The <em>Bhasma </em>is economic as the pharmaceutical processing of it is easy. In the pharmacological and therapeutic properties of this drug, it is mentioned that it has anti-epileptic activity. However there is no substantial evidence to prove the antiepileptic activity of <em>Kousheyashma</em>. Hence the present study is undertaken to experimentally evaluate the efficacy of <em>Kousheyashma Bhasma</em> in epilepsy.</p> <p class="Default"><strong> </strong>Antiepileptic activity was evaluated in Swiss albino mice by two methods namely Pentylenetetrazol (PTZ) induced seizure method and kindling PTZ induced seizure method. Mice selected based on exclusion and inclusion criteria were randomly allocated in to five groups. Mice were subjected for chemo convulsions by injecting PTZ intra peritoneal and observed for 35 minutes to analyze convulsion behaviors of mice</p> <p><strong></strong>kousheyashma Bhasma has shown statistically significant result in PTZ induced epileptic symptoms in Swiss albino mice.<strong> </strong></p> <p><strong><br /></strong></p>
 
Publication, Distribution, Etc. Indian Journal of Traditional Knowledge (IJTK)
2021-06-04 16:32:52
 
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http://op.niscair.res.in/index.php/IJTK/article/view/28165
 
Data Source Entry Indian Journal of Traditional Knowledge (IJTK); ##issue.vol## 20, ##issue.no## 2 (2021): Indian Journal of Traditional Knowledge
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJTK/article/download/28165/465486887