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Physical Stability and Bio-Efficacy Enhancement of Neem Kernel Aqueous Extract by Optimized Amount of Botanical Synergist for the Control of Early Stages of Mosquitoes

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Title Physical Stability and Bio-Efficacy Enhancement of Neem Kernel Aqueous Extract by Optimized Amount of Botanical Synergist for the Control of Early Stages of Mosquitoes
 
Creator Iqbal, Nusrat
Dubey, Saurabh
Kumar, Natish
Agrawal, Amrish
Kumar, Jitender
 
Subject Aqueous extract
Azadirachtin
Botanical stabilizer
Kikar Powder (KP)
Neem kernel powder (NKP)
Oil extract
 
Description 297-303
The aim of present study is to enhance the stability of physico-chemical characteristics of neem kernel aqueous extract by botanical stabilizer system. There are variety of bioactive constituents are present in neem which give broad-spectrum of insecticidal activity. Neem aqueous extract is commonly used and found very effective in pest control applications without harming the environment. However, due to hydrolytically unstable characteristics of neem active ingredients which results its lesser bioactivity and limits its usage in aqueous form. To overcome this un-stability issue oil extracted botanical stabilizer (Prosopis juliflora) (Junglee kikar)) were used in various ratios. In 70-30 (NKP-KP) composition (NKP- Neem kernel powder; KP- Kiker powder), neem aqueous extract was found stable without any turbidity, pH change, and fungal growth. Active ingredient, Azadirachtin was found stable with very less degradation i.e only 20–30% degradation. This may possibly be due to inhibition of hydrolytic reactions. Bio-efficacy evaluation data also showed improved and stable mosquito larvae mortality per cent i.e 75–90% with 8 µg/g LD50 value. The approach used in this study could be very useful in long term stability of neem kernel extract in various geographical conditions without adding toxic solvents or chemical compositions.
 
Date 2021-06-14T07:19:14Z
2021-06-14T07:19:14Z
2021-04
 
Type Article
 
Identifier 0975-1084 (Online); 0022-4456 (Print)
http://nopr.niscair.res.in/handle/123456789/57482
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source JSIR Vol.80(04) [April 2021]