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Design, synthesis and evaluation of new colourimetric chemosensors containing quinazolinones moiety for some cations detection in an aqueous medium and biological sample

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Title Design, synthesis and evaluation of new colourimetric chemosensors containing quinazolinones moiety for some cations detection in an aqueous medium and biological sample
 
Creator Algohary, Ayman M
Hassan, Mohamed M
Almalkic, Sami G
Al-Malkid, Esam S
 
Subject Chemosensor
Quinazolinone
Copper
Cadmium
Mercury
 
Description 755-766
The current project deals with designing and synthesizing of colourimetric chemosensors to detect the cations in the aqueous medium and biological sample. To achieve this goal a new series of quinazolinone derivatives have been synthesized via reaction of the novel 6-nitro-2-propyl-4H-benzo[d][1,3]oxazin-4-one 3 with selected nitrogen nucleophiles, namely, formamide, hydrazine hydrate, hydroxylamine hydrochloride, o-phenylendiamine, o-aminophenol and o-aminothiophenol, urea and/or thiourea. Structures of the new compounds have been investigated depending on their spectral data (IR, 1H and 13C NMR and MS) and elemental analyses. Some of the newly synthesized products exhibit significant response as chemosensors for a few cations detection.
 
Date 2021-06-25T07:22:48Z
2021-06-25T07:22:48Z
2021-05
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/57582
 
Language en_US
 
Rights CC Attribution-Noncommercial-No Derivative Works 2.5 India
 
Publisher NISCAIR-CSIR, India
 
Source IJC-B Vol.60B(05) [May 2021]