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<p class="TitleMain">Synthesis and biological evaluation of a series of novel benzofuran-2-carboxylate 1,2,3-triazoles</p><br />

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Title Statement <p class="TitleMain">Synthesis and biological evaluation of a series of novel benzofuran-2-carboxylate 1,2,3-triazoles</p><br />
 
Added Entry - Uncontrolled Name YADAV, JHILLU SINGH; INDRASHIL UNIVERSITY
Bhaskar, K ; Center for Semio Chemical Laboratory, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, India, School of Science, Indrashil University, Kadi, Mehsana 382 740, India
 
Uncontrolled Index Term 1,2,3-Triazoles, benzofuran-2-carboxylate, green chemistry, antimicrobial activity
 
Summary, etc. <p class="Abstract"><span lang="EN-GB">A facile and efficient synthetic route has been developed to substituted benzofuran-2-carboxylate 1,2,3-triazoles for the first time by reacting prop-2-yn-1-yl benzofuran-2-carboxylate with a variety of substituted aryl/benzyl azides in DMF/H<sub>2</sub>O system employing standard click reaction. This new method has the lead of good yields, inexpensive reagents, easily available, easy work-up, mild reaction conditions, and environmentally friendly reaction conditions. All these compounds have been characterized by modern spectral techniques such as IR, <sup>1</sup>H NMR, and mass spectroscopy, <em>etc</em>. Evaluation of synthesized compounds for antimicrobial activity against specific bacterial strains like <em>Staphylococcus aureus</em>, <em>Bacillus subtilis, Escherichia coli</em>, <em>Pseudomonas aeruginosa </em>along with antifungal activity against <em>Aspergillus niger</em> and <em>Sclerotium rolfsii</em> have been carried out.</span></p><br />
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-06-30 14:47:49
 
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http://op.niscair.res.in/index.php/IJCB/article/view/44911
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 5 (2021): Indian Journal of Chemistry- Section-B, (IJCB)
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJCB/article/download/44911/465543478
http://op.niscair.res.in/index.php/IJCB/article/download/44911/465543724
 
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