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Synthesis of new 2,2-dimethyl-2H-chromen derivatives as potential anticancer agents

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Title Synthesis of new 2,2-dimethyl-2H-chromen derivatives as potential anticancer agents
 
Creator Patel, Meghna
Noolvi, M N
Patel, Zinal
 
Subject Anticancer drugs
imidazothaidiazole
diaryl ketone
2,2-dimethyl-2H-chromen
 
Description 874-880
The synthesis of some new heterocyclic derivatives comprising imidazothaidiazole, diaryl ketone and chromen as
starting compound has been reported. The new series of chromen analogues have been synthesized. The reaction has been
monitored by Thin Layer Chromatography (TLC) using suitable mobile phase. The Rf values have been compared and the
melting points of derivatives determined. Further, these derivatives have been characterized and confirmed by IR, 1H NMR
and mass spectral (MS) studies. All the selected compounds submitted to National Cancer Institute (NCI) for in vitro
anticancer assay have been evaluated for their anticancer activity.
 
Date 2021-07-20T06:43:15Z
2021-07-20T06:43:15Z
2021-06
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/57737
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(06) [June 2021]