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Chemical composition, antimicrobial, and antioxidant activities of the essential oils from stem, leaves, and seeds of Caryopteris foetida (D. don) Thell.

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Title Chemical composition, antimicrobial, and antioxidant activities of the essential oils from stem, leaves, and seeds of Caryopteris foetida (D. don) Thell.
 
Creator Joshi, Archana
Pant, A K
Prakash, Om
Kumar, Ravendra
Stocki, Marcin
Isidorov, Valery A
 
Subject Anti-inflammatory
Antioxidant
BHT
Caryopteris foetida
δ-cadinene
 
Description 214-224
Caryopteris foetida (D. Don) Thell. also known as stinking blue beard is an aromatic shrub of family verbenaceae. The
essential oils from the leaf, stem, and seeds of C. foetida were extracted and analyzed in search of a novel compound. Over
73 constituents were identified from the essential oils of leaf, seeds, and stem. The major compound identified in the leaf oil
was δ-cadinene (15.4%) followed by β-caryophyllene (7.8%), (E)-β-farnesene (8.3%), γ-cadinene (7.5%), spathulenol
(7.2%), and τ-muurolol (5.1%). The stem oil predominantly consisted of methyl 7-methylcyclopenta[c]pyran-4-carboxylate
(15.8%) along with a significant amount of δ-cadinene (11.6%) and γ-cadinene (5.6%), whereas seed oil was characterized
by the presence of β-caryophyllene (14.3%) along with α-humulene (8.6%) and β-bisabolene (9.4%). The essential oils were
screened for their in vitro antioxidant potential in terms of radical scavenging, metal chelating and reducing assay. The leaf
oil exhibited strong DPPH radical scavenging (IC50 =5.1±0.2 μg/mL) and reducing activity (IC50 =3.6±0.5 μg/mL). The
antibacterial potential was tested against Salmonela typhimurium, Escherichia coli, Staphylococcus Aureus, and Bacillus
megaterium. Maximum activity was exhibited by the essential oils from the leaf and seed. The essential oils were also
analyzed for their in vitro anti-inflammatory activity by the protein denaturation method. Both the leaf and stem essential
oils exhibited good anti-inflammatory activity with IC50 value of 12.8±0.0 μg/mL and 17.3±0.0 μg/mL respectively.
 
Date 2021-07-28T05:02:40Z
2021-07-28T05:02:40Z
2021-06
 
Type Article
 
Identifier 0976-0512 (Online); 0976-0504 (Print)
http://nopr.niscair.res.in/handle/123456789/57758
 
Language en
 
Relation Int. cl. (2015.01)- A61K 36/00, A61K 36/85, A61K 127/00, A61K 131/00, A61K 135/00, A61P 39/00, A61P 31/00
 
Publisher NIScPR-CSIR, India
 
Source IJNPR Vol.12(2) [June 2021]