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Pharmacognostical and phytochemical blueprint of <em>Abroma augusta</em> L. stem bark

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Title Statement Pharmacognostical and phytochemical blueprint of <em>Abroma augusta</em> L. stem bark
 
Added Entry - Uncontrolled Name Hazra, Kalyan ; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
Dutta, Sreya ; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
Mandal, Achintya Kumar; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
Ravte, Rohit Kumar; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
Mitra, Achintya ; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
Hazra, Jayram ; Central Ayurvedic Research Institute of Drug Development, 4 CN Block, Sector-V, Bidhannagar, Calcutta 700091, West Bengal, India
None
 
Uncontrolled Index Term Pharmacognosy; Chemistry.
Abroma augusta; Betaine; FTIR; HPLC; HPTLC; Isolation; Microscopy.
 
Summary, etc. <p style="text-align: justify;">Uses of <em>Abroma augusta</em> L. stem and root are mentioned in traditional texts where the presence of the alkaloid, betaine in these parts is known. The study was undertaken to generate a pharmacognostical and phytochemical<strong> </strong>blueprint of <em>Abroma augusta</em> stem bark and detection of the bioactive alkaloid, betaine in it. Authenticated plant materials were subjected to pharmacognostical, physicochemical, and phytochemical studies. HPTLC, HPLC, and FTIR were used for chemical fingerprinting of the plant materials. Diagnostic features of <em>A. augusta</em> stem bark such as organoleptic evaluation, powder microscopic characters, fluorescence profile with various reagents were established. Phytochemical screening of different solvent extracts showed the presence of alkaloids, steroids, saponins, tannins, phenolics, glycosides, but fewer terpenoids, flavonoids, and carbohydrates. This was rationalized by FTIR spectroscopy of the chloroform extract that gave maximum extractive yield. HPTLC and HPLC fingerprint profiling with marker identification was generated. The alkaloid, betaine was isolated and identified by mass spectrum. The botanical and chemical screening suggested that <em>A. augusta</em> stem bark may be a potential substitute for the root or stem of the plant. However, further, bio-evaluations are required to ascertain its possible clinical applications. The generated profile may serve as a reference document in future for identification and authentication of the plant material.</p>
 
Publication, Distribution, Etc. Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]
2021-08-02 14:11:01
 
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http://op.niscair.res.in/index.php/IJNPR/article/view/24981
 
Data Source Entry Indian Journal of Natural Products and Resources (IJNPR) [Formerly Natural Product Radiance (NPR)]; ##issue.vol## 12, ##issue.no## 2 (2021): June 2021
 
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Nonspecific Relationship Entry http://op.niscair.res.in/index.php/IJNPR/article/download/24981/465477972
 
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