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Traditional methods of purification (detoxification process) for Schedule E poisonous drugs

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Title Traditional methods of purification (detoxification process) for Schedule E poisonous drugs
 
Creator L, Juliet
S, Karthik Raja
V L, Reena
V, Aarthi
K N, Sunil Kumar
P, Sathiyarajeswaran
K, Kanakavalli
 
Subject Purification process
Schedule E drugs
Siddha
Suthimuraigal
Toxicity
 
Description 740-748
Medicinal plants have different types of active phytochemicals, which are still in use, either in their crude form or after proper processing. Though most of the plant drugs are safe, few are poisonous and may cause immediate toxic effect or cumulative toxic effect for human health. There are 25 poisonous or toxic plants in Siddha texts listed in the Schedule E of Drugs and Cosmetics Act 1940. The concept of Suthimuraigal in Siddha not only covers the process of purification and detoxification of physical and chemical impurities but also minimizes the side effects and improves the potency/therapeutic efficacy of the purified drugs. The aim of this review is to perceive the importance of the Schedule E drugs through their immense uses to treat diseases and to flourish the knowledge of purification processes to detoxify the poisonous elements, thus enhancing and utilizing them in curing challenging diseases. The distinct purification methods mentioned in Ayurvedic journals have also been reviewed for possible information. Methods of Suthi are variable and some of the important Siddha Suthimuraigal are reviewed in this paper. The traditional methods of purification may combat the toxic effects like ulceration, swelling, giddiness, skin rashes, pruritis also, thus enhancing the efficacy of the drugs in healing various ailments. Since these poisonous plants have very high potential to treat diseases, the chemical changes which transpired during the Suthi are to be revealed in further studies such as quantitative and qualitative analysis after their purification before they are applied in medicines.
 
Date 2021-08-06T07:02:39Z
2021-08-06T07:02:39Z
2021-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/57877
 
Language en
 
Relation Int Cl.21: A61K 9/00, A61K 31/485, A61K 36/00, A61K 36/18, A61K 36/48, A61K 36/185, A61K 45/00
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.20(3) [July 2021]