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Shark cartilage (SC) and shark liver oil (SLO) treatment for lung damage via formaldehyde (FA) exposure

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Title Shark cartilage (SC) and shark liver oil (SLO) treatment for lung damage via formaldehyde (FA) exposure
 
Creator Akgül, Elvan
Dosay-Akbulut, Mine
Bozkurt, Fatih
Vurmaz, Ayhan
 
Subject FA
Lung damage
SC
SLO
 
Description 731-739
Formaldehyde reacts with amino acids in living organisms to form toxic intermediates that cause epithelial cell damage. In past epidemiological studies, a statistically significant relationship was found between FA and leukemia risks and occupational inhalation exposure. As a complementary and alternative medicine (CAM) technique or alternative medicine, shark cartilage (SC) and shark liver oil (SLO) are presented as a new and different alternative source in this study. In this study, the toxic effects of formaldehyde (FA) on lung and the protective effects of SC and SLO against these toxins have been investigated. For the experiment, 40 rats were classified as follows: 4, control group (experiment control); 6, the group that received FA but was not treated (treatment control); 15, the group that was given FA and SC for treatment; and the last 15 were the group that was given FA and SLO for treatment. Negative effects of FA on lung were evaluated biochemically, genetically and pathologically. In terms of therapeutic efficacy, SLO appears to be more effective in improving lung injury on the basis of genetic, pathological and biochemical findings, against to FA administration. The toxic effect of FA in lung and the therapeutic effect of SLO and SC were determined and we believe that our experimental model provided the desired goal and success on the basis of our work.
 
Date 2021-08-06T07:05:27Z
2021-08-06T07:05:27Z
2021-06
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/57878
 
Language en
 
Relation Int Cl.21: A23D 9/00, A61K 35/32, C11C 1/02, C11C 3/04, C12N 5/077, G01N 33/28
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.20(3) [July 2021]