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Screening of in vitro free radical scavenging activities of the fruit extracts of Psidium guajava L.

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Title Screening of in vitro free radical scavenging activities of the fruit extracts of Psidium guajava L.
 
Creator B H, Sowmya
D, Usha Anandhi
 
Subject Antioxidants
Free radicals
Fruit extract
Phenolic and flavonoid contents
Psidium guajava L.
 
Description 716-722
The objective of the current investigation was to evaluate the in vitro free radical scavenging properties of fruit extracts
of two varieties of Psidium guajava L. (PG) i.e., Lalit (LA) and Allahabad safeda (AS). The ethanolic fruit extracts of LA
and AS of PG were obtained from the soxhlet extraction procedure and the same was used for in vitro antioxidant assays.
Total phenols, flavonoid contents and free radical scavenging assays viz., ABTS, DPPH, nitric oxide and superoxide were
analysed at 100, 200, 300, 400, 500, 600 and 700 μg/mL concentrations. Phytochemical investigation exhibited higher
phenols, flavonoid contents in fruit extracts of LA compared to AS. The fruit extracts of PG showed remarkable ABTS,
DPPH, nitric oxide and superoxide free radical scavenging activity in a dose dependent manner. The fruit extracts of LA
exhibited higher free radical scavenging activity in contrast to AS. The present investigation revealed, a high in vitro
antioxidant property of LA due to its higher phenolic content. Hence, the fruit extract of Psidium guajava L. can be used in
therapeutics for the treatment of pathologic conditions involving free radicals.
 
Date 2021-08-06T07:11:42Z
2021-08-06T07:11:42Z
2021-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/57880
 
Language en
 
Relation Int Cl.21: A61K 31/05, A61K 39/00, A61K 45/06, A61P 39/06
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.20(3) [July 2021]