Record Details

Controlling progression of bacterial biofilm by herbal eye care formulation

NOPR - NISCAIR Online Periodicals Repository

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Field Value
 
Title Controlling progression of bacterial biofilm by herbal eye care formulation
 
Creator Rajput, Kanak
Yagnik, Bhupesh N
Kungwani, Neelam Amit
 
Subject Antimicrobial
Biofilm
Herbal eye care
Keratitis
Pseudomonas aeruginosa
Staphylococcus aureus
 
Description 679-684
Pseudomonas aeruginosa and Staphylococcus aureus causing common eye-infection ‘keratitis’ develop resistance to antibiotics by forming biofilm. Present study evaluates anti-biofilm properties of three commercially available eye care herbal formulations against P. aeruginosa and S. aureus. Eye drop formulations were tested for total phenolic content and antimicrobial activity. Biofilm growth over glass in the presence of herbal formulation was examined under fluorescence microscope. The herbal formulations rich in phenolics, tested at 10% (v/v) concentration showed growth inhibitory effect on planktonic cells. During biofilm mode of growth, 10% of herbal formulation caused considerable decline in growth of biofilm, although did not inhibit it completely. The response to different herbal formulations varied markedly among the different bacterial strains tested. Herbal components can significantly affect the surface topology of biofilms, thereby restricting the attachment of the cell to the substratum.
 
Date 2021-08-06T07:28:12Z
2021-08-06T07:28:12Z
2021-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/57885
 
Language en
 
Relation Int Cl.21: A61K 9/00, A61K 9/08, A61K 38/00, A61K 38/48, A61K 45/06, C12R 1/385, C12R 1/445
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.20(3) [July 2021]