Record Details

Effects of a multi route (oral and nasal) application of Lasunadya Ghrita (An ayurvedic formulation) in cases of primary depression: Inferences from a non randomized open label clinical trial

NOPR - NISCAIR Online Periodicals Repository

View Archive Info
 
 
Field Value
 
Title Effects of a multi route (oral and nasal) application of Lasunadya Ghrita (An ayurvedic formulation) in cases of primary depression: Inferences from a non randomized open label clinical trial
 
Creator Tiwari, Vandana
Rastogi, Sanjeev
Katiyar, Arvind
Nischal, Anil
 
Subject Ayurveda
Depression
Mental health
Traditional health care
 
Description 618-628
Mental diseases are rising globally. Depression is one among the most common mental disorders with an alarmingly high
incidence in India. Mental health care in general is suboptimal in India on account of inadequate resources and lack of
awareness. Pluralistic health care delivery model of India including its traditional health care services is less explored in
case of mental health for its possibility of adding value to the net mental health care delivery. The objective of the study was
to explore the efficacy of an ayurvedic formulation Lasunadya Ghrita (LG) in a multimodal application form in cases of
depression and to compare its efficacy with conventional care composed of Escitalopram, Etizolam and Zolpidem (EEZ)
provided in an allopathic psychiatric health care setting. Total 52 patients of depression allocated non randomly to Ayurveda
LG group and to Allopathy EEZ group were followed up for 4 weeks and evaluated on the basis of HAM-D and SF-36 mean
score changes of the participants on a pre and post basis and also for their intergroup comparisons. Statistically significant
changes in mean HAM-D and SF-36 Score were observed in a pre-post comparison in both the groups. An intergroup
comparison was non- significant for majority of HAM-D domains, barring a few showing the comparable effects of two
treatment approaches. Ayurvedic treatment was effective in work and energy domain and gastrointestinal symptoms.
Pre and post mean changes in HAM-D and SF-36 Score in two groups have shown significant changes in both the groups
suggestive of their individual efficacy. Insignificant difference in most domain scores of HAM-D and SF-36 in an inter
group comparison was suggestive of comparable efficacy of LG multi route application with EEZ allopathy care.
 
Date 2021-08-06T09:39:37Z
2021-08-06T09:39:37Z
2021-07
 
Type Article
 
Identifier 0975-1068 (Online); 0972-5938 (Print)
http://nopr.niscair.res.in/handle/123456789/57892
 
Language en
 
Relation Int Cl.21: A61K 9/00, A61K 9/20, A61K 36/00, A61K 36/185, A61K 36/9066, A61K 45/06
 
Publisher NIScPR-CSIR, India
 
Source IJTK Vol.20(3) [July 2021]