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Synthesis and spectroscopic investigation of binding of novel Thiazolo [2, 3-a] isoquinoline analog with bovine serum albumin

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Title Synthesis and spectroscopic investigation of binding of novel Thiazolo [2, 3-a] isoquinoline analog with bovine serum albumin
 
Creator Ranade, Prasanna B
Navale, Dinesh N
Zote, Santosh W
Kulal, Dnyaneshwar K
Sheikh, Mohmad V
Ramana, M M V
 
Subject DCC
Cyclisation
Fluorescence
Circular dichroism
BSA
 
Description 1081-1085
A condensation reaction between 1-cyclobutyl-3,4-dihydroisoquinoline and thioglycolic acid has been carried out using
DCC yields 10b-cyclobutyl-5,6-dihydro-2H-thiazolo [2, 3-a] isoquinolin-3(10bH)-one [CBIQTGA]. The synthesized
compound is characterised by using spectroscopic techniques. The interaction of CBIQTGA with bovine serum albumin has
been studied using UV spectroscopy, spectrofluorimetry and circular dichroism techniques.
 
Date 2021-08-23T10:44:03Z
2021-08-23T10:44:03Z
2021-08
 
Type Article
 
Identifier 0975-0975(Online); 0376-4710(Print)
http://nopr.niscair.res.in/handle/123456789/57923
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-A Vol.60A(08) [August 2021]