<p>Interaction studies of diglycine with aqueous solutions of sulphathiazole drug at different temperatures</p>
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Title Statement |
<p>Interaction studies of diglycine with aqueous solutions of sulphathiazole drug at different temperatures</p> |
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Added Entry - Uncontrolled Name |
Pal, A ; Department of Chemistry, Kurukshetra University, Kurukshetra 136 119 soni, surbhi ; Department of Chemistry, M.M.(Deemed to be) University, Mullana soni, surbhi ; Department of Chemistry, M.M.(Deemed to be) University, Mullana soni, surbhi ; Department of Chemistry, M.M.(Deemed to be) University, Mullana soni, surbhi ; department of chemistry, M.M. (Deemed to be) University mullana, Ambala, Haryana, India Financial support for this project (Sanction letter no. 01 (2187)/07/EMR-II) by the Government of India through the Council of Scientific and Industrial Research (CSIR), New Delhi is gratefully acknowledged. |
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Uncontrolled Index Term |
thermodynamics Diglycine, Sulphathiazole, Apparent molar volume, Apparent molar isentropic compression;. |
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Summary, etc. |
<p>The interactions of diglycine with sulphathiazole drug as a function of temperatures have been studied using volumetric and acoustic parameters. Densities and speeds of sound of diglycine in (0.001, 0.002,0.005, and 0.010) mol·kg<sup>-1</sup> aqueous solutions of sulphathiazole drug have been measured at five different temperatures of (288.15,293.15,298.15,303.15 and 308.15) K under 0.1MPa pressure. From density data, the apparent molar volume (V<sub>f</sub>), the partial molar volume ( ) and the standard partial molar volume of transfer ( ) for glycine from water to aqueous sulphathiazole solutions have been calculated. Partial molar isentropic compression and partial molar isentropic compression of transfer ( ) have been calculated from the speed of sound data. Transfer parameters by using cosphere overlap model have been explained from the point of view of concentration dependence of solute-solute and solute-solvent interactions. To draw the conclusion from the volumetric and acoustic data, limiting apparent molar expansion , as well as hydration numbers, have been studied. The calculated values of thermal expansion coefficient, , have small and positive values. All of these derived or calculated parameters are explained to understand the solvation behavior, mixing aspects and various types of interactions born in the ternary solutions of (drug + water + dipeptide) due to change in structure. We have also attempted to examine the temperature and concentration dependence of such interactions.<strong></strong></p> |
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Publication, Distribution, Etc. |
Indian Journal of Chemistry -Section A (IJCA) 2021-09-22 11:53:15 |
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Electronic Location and Access |
application/pdf http://op.niscair.res.in/index.php/IJCA/article/view/43539 |
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Data Source Entry |
Indian Journal of Chemistry -Section A (IJCA); ##issue.vol## 60, ##issue.no## 9 (2021): INDIAN JOURNAL OF CHEMISTRY- SECTION A |
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Language Note |
en |
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