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Endoscopic therapy for early colorectal cancer：a retrospective study

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Title Endoscopic therapy for early colorectal cancer：a retrospective study
 
Creator Wang, Yadan
Wu, Jing
Su, Hui
Liu, Kuiliang
Wei, Nan
Lin, Wu
Guo, Chun mei
Liu, Hong
Wang, Canghai
 
Subject Cold snare polypectomy
dysplasia
Endoscopic mucosal resection
Endoscopic submucosal dissection
Tumor
 
Description 745-750
Appropriate treatment options for early colorectal cancer
(ECRC) smaller than 20 mm remains controversial. Here, we
studied the efficacy and safety of endoscopic therapy for ECRC
smaller than 20 mm. About 191 patients with colorectal lesions
entered into our study from January 2017 to December 2019.
Lesions were divided into two groups according to sizes: smaller
than 10 mm group and 10-20 mm group. Most cases of ECRC
were found in the left colon (70.15%), and the male to female
ratio was 1.81:1. A very smaller proportion of colorectal lesions
smaller than 10 mm in size were submucosal carcinoma (0.077%),
whereas 3.85% of colorectal lesions between 10 mm and 20 mm
in size were submucosal carcinoma (P=0.049). Cold snare
polypectomy (CSP) was found to be a safe and efficient for
lesions smaller than 10 mm. For the lesions smaller than 10 mm,
the rate of en bloc resection reached 100%, whereas only 81.82%
of the lesions of 10-20 mm in size could be resected en bloc and
for these cases, endoscopic mucosal resection (EMR) were better
therapeutic options. Endoscopic CSP is an appropriate therapeutic
approach for ECRC of less than 10 mm in size, whereas for
lesions smaller than 10 mm in size but with submucosal
infiltration, EMR should be considered. For submucosal
carcinoma (SM-carcinoma), endoscopic submucosal dissection
(ESD) or surgery should be considered as better options.
 
Date 2021-10-04T07:02:11Z
2021-10-04T07:02:11Z
2021-10
 
Type Article
 
Identifier 0975-1009 (Online); 0019-5189 (Print)
http://nopr.niscair.res.in/handle/123456789/58211
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJEB Vol.59(10) [October 2021]