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<p>Preparation, characterization, antibacterial, antifungal and antioxidant activities of novel pyrazole-thiazole derivatives</p>

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Title Statement <p>Preparation, characterization, antibacterial, antifungal and antioxidant activities of novel pyrazole-thiazole derivatives</p>
 
Added Entry - Uncontrolled Name Shah, Purvesh J; Department of Chemistry, K K Shah Jarodawala Maninagar Science College, Maninagar, Ahmedabad 380 008, India
 
Uncontrolled Index Term Pyrazole-thiazole, spectral studies, antimicrobial activity, antioxidant activity
 
Summary, etc. <p style="text-align: justify;">In the present study, 4-((1<em>H</em>-benzo[d][1,2,3]triazol-1-yl)methylamino)-N-(2,3-diphenyl-5-aryl-3,3a-dihydro-2<em>H</em>-pyrazolo [3,4-d]thiazol-6(5<em>H</em>)-yl)benzamide <strong>IVa-h</strong> has been synthesized by reaction between various 4-((1<em>H</em>-benzo[d][1,2,3]triazol-1-yl) methylamino)-N-(5-arylidene-4-oxo-2-phenylthiazolidin-3-yl)benzamides <strong>IIa-h</strong> with phenyl hydrazine. The reaction of 4-((1<em>H</em>-benzo[d][1,2,3]triazol-1-yl)methylamino)-N-(4-oxo-2-aryl thiazolidin -3-yl) benzamide <strong>Ia-h</strong> with benzaldehyde yields <strong>IIa-h</strong>. All the newly prepared compounds have been characterized by various spectroscopic techniques and screened for their <em>in vitro</em> antimicrobial and antioxidant activity. The investigation of anti microbial screening data reveals that most of the compounds tested have demonstrated moderate to good activity. Most of the heterocyclic derivatives bearing two hydroxyl groups on the phenyl ring show excellent antioxidant activity in comparison with ascorbic acid.</p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-10-14 15:19:06
 
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http://op.niscair.res.in/index.php/IJCB/article/view/31336
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 9 (2021): Indian Journal of Chemistry- Section-B, (IJCB)
 
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