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<p>An efficient synthesis of 1, 4- disubstituted-3-methyl pyrazolo [4, 3-e]-pyrido [1, 2-a] pyrimidines <em>via</em> Michael addition and cycloelimination reactions</p><br />

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Title Statement <p>An efficient synthesis of 1, 4- disubstituted-3-methyl pyrazolo [4, 3-e]-pyrido [1, 2-a] pyrimidines <em>via</em> Michael addition and cycloelimination reactions</p><br />
 
Added Entry - Uncontrolled Name Tiwari, Shailendra ; , university of Allahabad
Ahamd, Akeel ; Department of Chemistry, Mirza Ghalib College, Gaya, 823 001, India
 
Uncontrolled Index Term 1, 4-Disubstitutedaroyl/aroyloxy methyl, Schiff base, pyrazolo, pyrido [1,2-a]pyrimidine, antimicrobial, antibacterial activity, antifungal activity
 
Summary, etc. <p style="text-align: justify;">A new series of novel 1, 4-disubstituted-3-methyl pyrazolo [4,3-e]-pyrido [1,2-a] pyrimidines have been synthesized from a common intermediate, in good yields. These compounds have been screened for their antibacterial and antifungal activity against different pathogenic strains of bacteria and fungi. The minimum inhibitory concentration (MBC) and minimum fungicidal concentration (MFC) have been determined for the test compounds as well as for reference standards. Compounds <strong>3d</strong>, <strong>3e</strong>, <strong>3f</strong>, <strong>3h</strong> have shown good antibacterial activity whereas compounds <strong>3a</strong>, <strong>3b</strong>, <strong>3c</strong>, <strong>3g</strong> have displayed better antifungal activity.</p><p style="text-align: justify;"> </p>
 
Publication, Distribution, Etc. Indian Journal of Chemistry -Section B (IJC-B)
2021-10-14 15:19:06
 
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http://op.niscair.res.in/index.php/IJCB/article/view/38835
 
Data Source Entry Indian Journal of Chemistry -Section B (IJC-B); ##issue.vol## 60, ##issue.no## 9 (2021): Indian Journal of Chemistry- Section-B, (IJCB)
 
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