Synthesis and biological evaluation of azetidinone derivatives with pyrazolone moiety
NOPR - NISCAIR Online Periodicals Repository
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Title |
Synthesis and biological evaluation of azetidinone derivatives with pyrazolone moiety
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Creator |
Bhabhor, Falguni
Dabhi, Harish |
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Subject |
2-Azetidinone
pyrazolone Schiff base antimicrobial activity |
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Description |
1396-1399
A Schiff base has been prepared by the reaction of 4-acetyl-5-methyl-2-(4-methylphenyl)-2,4-dihydro-3H-pyrazole-3-one with different substituted amines. Treatment of this Schiff base with chlorobactyl chloride affords the corresponding azetidinone in good yield. All the new compounds have been characterized by IR, 1H NMR, GC-MS and elemental analysis. The antibacterial activity of these compounds has been determined with the reference of standard drug. |
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Date |
2021-10-20T10:05:15Z
2021-10-20T10:05:15Z 2021-10 |
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Type |
Article
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Identifier |
0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58318 |
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Language |
en
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Publisher |
NIScPR-CSIR, India
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Source |
IJC-B Vol.60B(10) [October 2021]
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