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Synthesis and biological evaluation of azetidinone derivatives with pyrazolone moiety

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Title Synthesis and biological evaluation of azetidinone derivatives with pyrazolone moiety
 
Creator Bhabhor, Falguni
Dabhi, Harish
 
Subject 2-Azetidinone
pyrazolone
Schiff base
antimicrobial activity
 
Description 1396-1399
A Schiff base has been prepared by the reaction of 4-acetyl-5-methyl-2-(4-methylphenyl)-2,4-dihydro-3H-pyrazole-3-one with different substituted amines. Treatment of this Schiff base with chlorobactyl chloride affords the corresponding azetidinone in good yield. All the new compounds have been characterized by IR, 1H NMR, GC-MS and elemental analysis. The antibacterial activity of these compounds has been determined with the reference of standard drug.
 
Date 2021-10-20T10:05:15Z
2021-10-20T10:05:15Z
2021-10
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58318
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(10) [October 2021]