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A convenient metal free approach towards the synthesis of dihydropyrimidones mediated by achiral nicotinic acid without solvent

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Title A convenient metal free approach towards the synthesis of dihydropyrimidones mediated by achiral nicotinic acid without solvent
 
Creator Imon, Mohinuddin Khan
Kamma, Koteswara R
Islam, M N
Roy, Harendra N
 
Subject Dihydropyrimidones
nicotinic acid
solvent-free
N-heterocycles
metal-free
 
Description 1378-1384
A very simple arrangement of Biginelli’s condensation reaction of 1,3-dicarbonyl compound, aromatic / aliphatic
aldehyde and urea / thiourea has been performed in a convenient way by using nicotinic acid without any solvent and under
ambient conditions. This approach of pyrimidone synthesis is simple, versatile, metal-free, high yielding and
environmentally benign.
 
Date 2021-10-20T10:13:51Z
2021-10-20T10:13:51Z
2021-10
 
Type Article
 
Identifier 0975-0983(Online); 0376-4699(Print)
http://nopr.niscair.res.in/handle/123456789/58320
 
Language en
 
Publisher NIScPR-CSIR, India
 
Source IJC-B Vol.60B(10) [October 2021]